Monanchomycalins A and B, unusual guanidine alkaloids from the sponge Monanchora pulchra SCIE SCOPUS

Cited 33 time in WEB OF SCIENCE Cited 35 time in Scopus
Title
Monanchomycalins A and B, unusual guanidine alkaloids from the sponge Monanchora pulchra
Author(s)
Makarieva, Tatyana N.; Tabakmaher, Ksenya M.; Guzii, Alla G.; Denisenko, Vladimir A.; Dmitrenok, Pavel S.; Kuzmich, Alexandra S.; Lee, Hyi-Seung; Stonik, Valentin A.
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2012-08-08
Abstract
New pentacyclic guanidine alkaloids, monanchomycalins A (1) and B (2) were isolated from the marine sponge, Monanchora pulchra and their structures elucidated using NMR, HRMALDI-TOF-MS, and HRESI MS, as well as by chemical transformations of 1. Compounds 1 and 2 exhibited potent cytotoxic activities against HL-60 human leukemia cells with IC50 values of 120 and 140 nM, respectively. (C) 2012 Elsevier Ltd. All rights reserved.
ISSN
0040-4039
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3475
DOI
10.1016/j.tetlet.2012.05.162
Bibliographic Citation
TETRAHEDRON LETTERS, v.53, no.32, pp.4228 - 4231, 2012
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Subject
PTILOMYCALIN-A; CRAMBE-CRAMBE; CRAMBESCIDIN-800; HIV-1
Keywords
Pentacyclic guanidine alkaloids; Monanchomycalins; Spermidine; Marine sponge; Monanchora pulchra
Type
Article
Language
English
Document Type
Article
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
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