Monanchomycalins A and B, unusual guanidine alkaloids from the sponge Monanchora pulchra SCIE SCOPUS
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- Title
- Monanchomycalins A and B, unusual guanidine alkaloids from the sponge Monanchora pulchra
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
- Alternative Author(s)
- 이희승
- Publication Year
- 2012-08-08
- Abstract
- New pentacyclic guanidine alkaloids, monanchomycalins A (1) and B (2) were isolated from the marine sponge, Monanchora pulchra and their structures elucidated using NMR, HRMALDI-TOF-MS, and HRESI MS, as well as by chemical transformations of 1. Compounds 1 and 2 exhibited potent cytotoxic activities against HL-60 human leukemia cells with IC50 values of 120 and 140 nM, respectively. (C) 2012 Elsevier Ltd. All rights reserved.
- ISSN
- 0040-4039
- Bibliographic Citation
- TETRAHEDRON LETTERS, v.53, no.32, pp.4228 - 4231, 2012
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Subject
- PTILOMYCALIN-A; CRAMBE-CRAMBE; CRAMBESCIDIN-800; HIV-1
- Keywords
- Pentacyclic guanidine alkaloids; Monanchomycalins; Spermidine; Marine sponge; Monanchora pulchra
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
