First description of ColE-type plasmid in Aeromonas spp. carrying quinolone resistance (qnrS2) gene
SCIE
SCOPUS
Cited 22 time in
WEB OF SCIENCE
Cited 25 time in
Scopus
-
Title
- First description of ColE-type plasmid in Aeromonas spp. carrying quinolone resistance (qnrS2) gene
-
Author(s)
- Han, J. E.; Kim, J. H.; Choresca, C. H., Jr.; Shin, S. P.; Jun, J. W.; Chai, J. Y.; Park, S. C.
-
Alternative Author(s)
- 김지형
-
Publication Year
- 2012-10
-
Abstract
- Aims: Isolation and full sequence analysis of ColE-type plasmid, which carries the qnrS2 gene. Methods and Results: Quinolone resistance (qnrS2) gene-carrying plasmids were isolated from Aeromonas sobria and Aeromonas hydrophila strains, and plasmid sequencing was achieved by a primer-walking approach. The total sizes of these plasmids (pAQ2-1 and pAQ2-2) were 6900 bp and 6903 bp, respectively, and they were 99.1% identical to each other. The genes (oriV and repA) for plasmid replication were organized similar to the corresponding genes in the ColE2-type plasmids, pAsa3 and pAsa1, isolated from Aeromonas salmonicida subsp. salmonicida, but the gene (mobA) for mobilization was homologue to ColE1-type plasmid (pAsa2) from Aer. salmonicida subsp. salmonicida. Additionally, the qnrS2 gene was part of a mobile insertion cassette element in the plasmid. Conclusions: Two plasmids were assumed to be the same plasmid, and this identification of a plasmid-mediated qnrS2 gene from the two different strains underlines a possible diffusion of these resistance determinants in an aquaculture system. Significance and Impact of the Study: This is the first finding of the ColE-type plasmid carrying the qnrS2 gene.
-
ISSN
- 0266-8254
-
URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/3450
-
DOI
- 10.1111/j.1472-765X.2012.03293.x
-
Bibliographic Citation
- LETTERS IN APPLIED MICROBIOLOGY, v.55, no.4, pp.290 - 294, 2012
-
Publisher
- WILEY
-
Subject
- FLUOROQUINOLONE RESISTANCE; SALMONELLA; DETERMINANTS; MECHANISMS; STRAINS; WATER; PREVALENCE; FISH
-
Keywords
- Aeromonas spp; ColE2-type; qnrS2 gene; quinolone resistance
-
Type
- Article
-
Language
- English
-
Document Type
- Article
- Files in This Item:
-
There are no files associated with this item.
Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.