Accumulation of p,p-DDT in marine organisms exposed to DDT and TBT

Accumulation of p,p-DDT in marine organisms exposed to DDT and TBT
홍상희; 심원준; 신영범; 전중균; 김분희; 오재룡
KIOST Author(s)
Hong, Sang Hee(홍상희)Shim, Won Joon(심원준)
Publication Year
Olive flounder [Paralichthyls olivaceus], bivalve [Gomphina(Macridiscus) veneriformis melanaegis] and gastropod [Thais chlavigera] were exposed to DDT with (or without) TBT for evaluating the effect of mixed-chemical exposure for DDT accumulation. All target species showed apparent increase of DDT compounds according to exposure period and simultaneously its degradation products (DDD, DDE, DDMU, DBP) also increased. Among the metabolites, DDD contributed to the largest portion with 43 – 97%, and followed by DDE (1 – 55%), DDMU (0.3 – 2%), and DBP (0.2 – 3.6). Although muscle, serum and bile showed similar patterns between two exposure groups, liver of olive flounder showed the different DDT accumulation pattern between two exposure groups. The metabolization of DDT exceeded its accumulation after 30-exposure day in DDT exposure group (DDT / åDDT = 0.15, at 60-exposure day), while the reduction of metabolic activity was found in liver of olive flounder of DDT + TBT exposure group (DDT / åDDT = 0.83, at 60-exposure day). Similar effect was also observed in gastropod but not in bivalve. The reduction of DDT biodegradation in liver of olive flounder and gastropod provide that TBT suppress induction or activity of cytochrome P450 enzyme involved to DDT detoxication.
Bibliographic Citation
SETAC(Society of Environmental Toxicology and Chemistry) 23rd Annual Meeting in North America, pp.316, 2002
Society of Environmental Toxicology and Chemistry
Society of Environmental Toxicology and Chemistry
Related Researcher
Research Interests

Microplastic pollution,Persistent Organic Pollutants,Oil Pollution,미세플라스틱 오염,잔류성 유기오염물질,유류오염

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