Diversity of Secondary Metabolites from Marine Bacillus Species: Chemistry and Biological Activity
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- Diversity of Secondary Metabolites from Marine Bacillus Species: Chemistry and Biological Activity
- Mondol, Muhammad Abdul Mojid; Shin, Hee Jae; Islam, Mohammad Tofazzal
- KIOST Author(s)
- Shin, Hee Jae(신희재)
- Marine Bacillus species produce versatile secondary metabolites including lipopeptides, polypeptides, macrolactones, fatty acids, polyketides, and isocoumarins. These structurally diverse compounds exhibit a wide range of biological activities, such as antimicrobial, anticancer, and antialgal activities. Some marine Bacillus strains can detoxify heavy metals through reduction processes and have the ability to produce carotenoids. The present article reviews the chemistry and biological activities of secondary metabolites from marine isolates. Side by side, the potential for application of these novel natural products from marine Bacillus strains as drugs, pesticides, carotenoids, and tools for the bioremediation of heavy metal toxicity are also discussed.
- MARINE DRUGS, v.11, no.8, pp.2846 - 2872, 2013
- COMPLETE GENOME SEQUENCE; CYCLIC LIPOPEPTIDE; NATURAL-PRODUCTS; FUNCTIONAL-CHARACTERIZATION; GASTROPROTECTIVE ACTIVITY; AMYLOLIQUEFACIENS FZB42; STRUCTURE ELUCIDATION; MICROBIAL PRODUCTS; CHEMICAL NATURE; GENE CLUSTERS
- bioactive compounds; macrolactins; detoxification; biosynthesis; carotenoids; biopesticides
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