The potential antioxidant effect of Sargassum fulvellum extract treatment: a study on Ins-1, VSMC, Hep2G cells for anti-diabetes, anti-arteriosclerosis, and anti-hypertension effects

Title
The potential antioxidant effect of Sargassum fulvellum extract treatment: a study on Ins-1, VSMC, Hep2G cells for anti-diabetes, anti-arteriosclerosis, and anti-hypertension effects
Author(s)
우선옥; 김정하; 염승식; 이택견
KIOST Author(s)
Yum, Seungshic(염승식)Lee, Taek Kyun(이택견)
Publication Year
2007-03-26
Abstract
Recently seaweed resources are used as ral materials for food and cosmetics due to their antioxidant and antibacterial activitties. Macroalgae is an important primary producer in coastal region and the diversity and health status of macroalgae population can be a significant indicator for marine ecosystem. Specifically seaweed forest consisted of macro brown algae (kelp) shows the similar function of land forest and provides spawning spot, refuge place as well as habitat for various marine organisms. Also seaweeds have been studied as new sources of a variety of compounds showing biological activities of potential medicinal value. Sargassum fulvellum (Sargassaceae, Fucales) is brown macroalgae and is cultured for food for human and animal in Korea. In this study, we aimed to investigate anti-oxidative effect of Sargassum fulvellum and examine the antioxidative activity-induced further effects on neural cell, INS-1, vascular smooth muscle cell, and HepG2 cell. The Sargassum fulvellum fraction showing high antioxidative effect induced insulin gene expression, and showed inhibitory effect on neural cell death by Fe and Zn as well as vascular smooth muscle cell and HepG2 cell proliferation by PDGF-BB. These results suggest that Sargassum fulvellum could be considered as a potential source for the antioxidant which may be used as natural antioxidant or raw materials of food supplement.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/30641
Bibliographic Citation
XIXth International Seaweed Symposium, pp.196 - 197, 2007
Publisher
The Japanese Society of Marine Biotechnology
Type
Conference
Language
English
Publisher
The Japanese Society of Marine Biotechnology
Related Researcher
Research Interests

Marine virus,Marine pathogens,해양바이러스,해양병원체

Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse