Novel Angiogenesis Inhibitor from Streptomyces sp. Isolated from a Marine Sponge

DC Field Value Language
dc.contributor.author 신희재 -
dc.contributor.author 이희승 -
dc.contributor.author 권호정 -
dc.contributor.author 박정열 -
dc.date.accessioned 2020-07-17T04:31:32Z -
dc.date.available 2020-07-17T04:31:32Z -
dc.date.created 2020-02-11 -
dc.date.issued 2007-05-11 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/30586 -
dc.description.abstract Angiogenesis, the process of new blood vessel formation, is crucial for the development and progression of pathophysiological changes associated with a variety of disorders, including various cancers, tumor metastases, and retinopathies. Malignant angiogenesis plays a critical role in several fatal diseases including cancer, vascular insufficiency, diabetic retinopathy, and rheumatoid arthritis by a normal delivering mechanism of oxygen and nutrients to cell and tissue. Because tumor angiogenesis caused by angiogenic inducers is the most critical factor in the growth of solid tumors, as well as their invasion and metastasis, early control of angiogenesis may be a promising therapeutic strategy for the related diseases. As part of our ongoing program to develop the biomedical potential of marine microorganisms, we isolated a new angiogenesis inhibiotr from the fermentation broth of a marine Streptomyces sp. The isolation, structure determination, and anti-angiogenesis activity of the new compound from marine actinomycete will be presented. -
dc.description.uri 2 -
dc.language English -
dc.publisher 대한약학회 -
dc.relation.isPartOf The Pharmaceutical Society of Korea -
dc.title Novel Angiogenesis Inhibitor from Streptomyces sp. Isolated from a Marine Sponge -
dc.type Conference -
dc.citation.conferencePlace KO -
dc.citation.endPage 269 -
dc.citation.startPage 269 -
dc.citation.title The Pharmaceutical Society of Korea -
dc.contributor.alternativeName 신희재 -
dc.contributor.alternativeName 이희승 -
dc.identifier.bibliographicCitation The Pharmaceutical Society of Korea, pp.269 -
dc.description.journalClass 2 -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 2. Conference Papers
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