Bioprocess Intensification for Production of Mycosporine-Like Amino Acids Through Radiofrequency Bioreactor

Abstract

In the context of marine biochemical systems, opportunities exist for the development of novel bioreactors, with optimization and conversion of current technologies for improvement in the production yield. Mycosporine-like amino acids (MAAs) are small, ultraviolet (UV) absorbing molecules which are widely distributed in marine and freshwater organisms. Due to their unique UV absorption properties there are many possibilities to use them in cosmetic industries as a UV blocking ingredient. Looking at their suitability in cosmetic industry, there is a need to increase the production yield of MAAs. In the present study we investigated Glut-1 gene transformedChlamydomonas hedleyi microalgae for the effective production of as a MAAs, which are present in the microalgae, by applying radiofrequency (RF). It is observed that, the biomass got enhanced with glucose in culture media. However, after RF treatment, the MAAs production yield found to be further increased during culturing in modified RF bioreactors. Hence, the purified extracts of MAAs, such as Shinorine and Porphyra, can be utilized in cosmetic industries.) are small, ultraviolet (UV) absorbing molecules which are widely distributed in marine and freshwater organisms. Due to their unique UV absorption properties there are many possibilities to use them in cosmetic industries as a UV blocking ingredient. Looking at their suitability in cosmetic industry, there is a need to increase the production yield of MAAs. In the present study we investigated Glut-1 gene transformedChlamydomonas hedleyi microalgae for the effective production of as a MAAs, which are present in the microalgae, by applying radiofrequency (RF). It is observed that, the biomass got enhanced with glucose in culture media. However, after RF treatment, the MAAs production yield found to be further increased during culturing in modified RF bioreactors. Hence, the purified extracts of MAAs, such as Shinorine and Porphyra, can be utilized in cosmetic industries.