Diketopiperazines from Marine Actinomycetes

Title
Diketopiperazines from Marine Actinomycetes
Author(s)
유병철; 이정수; 한종우; 이희승; 신희재
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2007-10-12
Abstract
Diketopiperazines (DKPs) are a class of cyclic compounds that result from peptide bonds between two amino acids to form a lactam and are widespread as metabolites of various bacteria and fungi. Diketopiperazines possess powerful and useful biological activities including anticancer and antimicrobial activities. As marine environmental conditions are extremely different from terrestrial ones, it is surmised that marine actinomycetes have different characteristics from those of terrestrial counterparts and, therefore, might produce different types of bioactive compounds.In our ongoing research to develop the biomedical potential of marine actinomycetes, we isolated several diketopiperazines from the fermentation broth of a marine actinomycetes. The isolation, structure determination, and biological activities of diketopiperazines from marine actinomycetes will be presented.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/30316
Bibliographic Citation
International Meeting of the Federation of Korean Microbiological Societies, pp.212, 2007
Publisher
The Federation of Korean Microbiological Societies
Type
Conference
Language
English
Publisher
The Federation of Korean Microbiological Societies
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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