해양환경으로부터 효소 개발

DC Field Value Language
dc.contributor.author 김상진 -
dc.contributor.author 강성균 -
dc.contributor.author 우정희 -
dc.contributor.author 권개경 -
dc.contributor.author 이정현 -
dc.contributor.author 이현숙 -
dc.contributor.author 차선신 -
dc.date.accessioned 2020-07-17T00:50:19Z -
dc.date.available 2020-07-17T00:50:19Z -
dc.date.created 2020-02-11 -
dc.date.issued 2008-09-01 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/29826 -
dc.description.abstract The ocean covers more than 70% of the Earth’s surface. Diverse microorganisms have been found from various marine environments and represent a vast untapped resource with potential benefits in different areas such as medicine, aquaculture and fisheries, industry, research tools and environmental applications. At Marine Biotechnology Research Center in KORDI (www.megrc.re.kr), we have been collecting samples from a variety of marine environments such as cold seep, hydrothermal vent, deep sea, tidal flat area and so on to span various physical, chemical and biological environment. The collected samples were treated to isolate microorganisms, followed by partial sequencing of 16S rRNA gene and screening of various enzyme activities. To speed up the process of developing useful and novel enzymes from marine microorganisms, genomic approach has been applied. Briefly, whole genome sequence of microorganisms with desirable activities was being determined by pyro-sequencing or shotgun sequencing method, followed by bioinformatic analysis, cloning and characterization studies. At the same time, marine microorganims whose genome sequences were being determined by Moore Foundation or other genome projects were collected on the basis of bilateral collaboration and also followed by bioinformatic analysis, cloning and characterization of the candidate ORFs. We are currently focusing on developing enzymes with extreme biophysical properties or enantioselectivity. We found that the genomic approach is promising to provide opportunities to find novel enzymes with desirable activities at a short period time. -
dc.description.uri 1 -
dc.language English -
dc.publisher International Society of Extremophile -
dc.relation.isPartOf Extremophile 2008 -
dc.title 해양환경으로부터 효소 개발 -
dc.title.alternative DEVELOPMENT OF ENZYMES FROM MARINE ENVIRONMENT -
dc.type Conference -
dc.citation.conferencePlace US -
dc.citation.endPage 137 -
dc.citation.startPage 137 -
dc.citation.title Extremophile 2008 -
dc.contributor.alternativeName 김상진 -
dc.contributor.alternativeName 강성균 -
dc.contributor.alternativeName 우정희 -
dc.contributor.alternativeName 권개경 -
dc.contributor.alternativeName 이정현 -
dc.contributor.alternativeName 이현숙 -
dc.contributor.alternativeName 차선신 -
dc.identifier.bibliographicCitation Extremophile 2008, pp.137 -
dc.description.journalClass 1 -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 2. Conference Papers
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