Chitosan silver nano composites (CAgNCs) as antibacterial agent against fish pathogenic Edwardsiella tarda SCOPUS KCI

Title
Chitosan silver nano composites (CAgNCs) as antibacterial agent against fish pathogenic Edwardsiella tarda
Author(s)
Dananjaya, S.H.S.; Godahewa, G.I.; Lee, Y.; Cho, J.; Lee, J.; De Zoysa, M.
KIOST Author(s)
Lee, Young Deuk(이영득)
Publication Year
2014
Abstract
Recently nano particles have proven for wide array of bioactive properties. In the present study, antibacterial properties of chitosan silver nano composites (CAgNCs) were investigated against fish pathogenic Edwardsiella tarda. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of CAgNCs against E. tarda were 25 µg/mL and 125 µg/mL, respectively. The field emission scanning electron microscope (FE-SEM) image of CAgNCs treated E. tarda showed the strongly damaged bacteria cells than non-treated bacteria. Furthermore, treatment of CAgNCs induced the level of intracellular reactive oxygen species (ROS) in E. tarda cells in concentration and time dependent manner suggesting that it may generate oxidative stress leading to bacterial cell death. In addition, MTT assay results showed that the lowest cell viability at 100 µg/mL of CAgNCs treated E. tarda. Overall results of this study suggest that CAgNCs is a potential antibacterial agent to control pathogenic bacteria. © 2014, Korean Society of Veterinary Clinics. All rights reserved.
ISSN
1598-298X
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/2937
Bibliographic Citation
Journal of Veterinary Clinics, v.31, no.6, pp.502 - 506, 2014
Publisher
Korean Society of Veterinary Clinics
Keywords
Antimicrobial agents; Chitosan-silver nanocomposites; Edwardsiella tarda; Edwardsiellosis; Reactive oxygen species
Type
Article
Language
English
Document Type
Article
Publisher
Korean Society of Veterinary Clinics
Related Researcher
Research Interests

Marine Biotechnology,Marine Organism Molecular genetics,Marine Bacterial engineering,해양생물공학,해양생물분자유전학,해양미생물공학

Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse