Heterologous microarray hybridization used to differential gene expression profiling in Benzo[a]pyrene exposed marine medaka
DC Field | Value | Language |
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dc.contributor.author | 원효경 | - |
dc.contributor.author | Woo S | - |
dc.contributor.author | Park H | - |
dc.contributor.author | 염승식 | - |
dc.date.accessioned | 2020-07-16T22:30:40Z | - |
dc.date.available | 2020-07-16T22:30:40Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2009-09-22 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/29341 | - |
dc.description.abstract | Differential gene expression profiling was carried out in the hepatic tissue of marine medaka fish, Oryzias javanicus, after exposure to benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon (PAH), by heterologous hybridization using a medaka cDNA microarray. Forty kinds of differentially expressed candidate genes, with 24 induced and 16 repressed in their gene expressions (P < 0.01), which were associated with cell cycle, development, endocrine/reproduction, immune, metabolism, nucleic acid/protein binding, signal transduction, and non-categorized. The presumptive physiological changes induced by B[a]P exposure could be deduced after considering the biological function of each gene candidates. The identified genes could be used as molecular biomarkers for biological responses to B[a]P contamination in an aquatic environment. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | Molecular and Cellular Toxicology | - |
dc.relation.isPartOf | The Joint International Symposium of 5th International Conference on Toxicogenomics (ICT) and 2nd Toxicogenomics Integrated Environmental Science (TIES) | - |
dc.title | Heterologous microarray hybridization used to differential gene expression profiling in Benzo[a]pyrene exposed marine medaka | - |
dc.type | Conference | - |
dc.citation.conferencePlace | KO | - |
dc.citation.endPage | 69 | - |
dc.citation.startPage | 69 | - |
dc.citation.title | The Joint International Symposium of 5th International Conference on Toxicogenomics (ICT) and 2nd Toxicogenomics Integrated Environmental Science (TIES) | - |
dc.contributor.alternativeName | 원효경 | - |
dc.contributor.alternativeName | 염승식 | - |
dc.identifier.bibliographicCitation | The Joint International Symposium of 5th International Conference on Toxicogenomics (ICT) and 2nd Toxicogenomics Integrated Environmental Science (TIES), pp.69 | - |
dc.description.journalClass | 1 | - |