Diketopiperazines from the Culture Broth of a Marine Actinomycete Promicromonospora sp.

Title
Diketopiperazines from the Culture Broth of a Marine Actinomycete Promicromonospora sp.
Author(s)
김지혜; 한종우; Mojid Mondol; 이희승; 이연주; 신희재
KIOST Author(s)
Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)Shin, Hee Jae(신희재)
Publication Year
2009-10-15
Abstract
Diketopeperazines (DKPs) and their derivatives are widely distributed in nature as secondary metabolites. They have a wide variety of biological activities including antitumor, antiviral, antifungal and antibacterial activities.As marine environmental conditions are extremely different from terrestrial ones, it is surmised that marine actinomycetes have different characteristics from those of terrestrial counterparts and, therefore, might produce different types of bioactive compounds. In our on-going research to develop the biomedical potential of marine actinomycetes, we isolated several diketopiperazines from the fermentation broth of a marine actinomycete, Promicromonospora sp. strain. The structures of these diketopiperazines were determined using spectroscopic methods. The fermentation, isolation, and structure elucidation of diketopiperazines will be presented.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/29329
Bibliographic Citation
The Pharmaceutical Society of Korea, pp.195, 2009
Publisher
The Pharmaceutical Society of Korea
Type
Conference
Language
English
Publisher
The Pharmaceutical Society of Korea
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