Gageotetrins A-C, Noncytotoxic Antimicrobial Linear Lipopeptides from a Marine Bacterium Bacillus subtilis SCIE SCOPUS
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- Title
- Gageotetrins A-C, Noncytotoxic Antimicrobial Linear Lipopeptides from a Marine Bacterium Bacillus subtilis
- KIOST Author(s)
- Lee, Min Ah(이민아); Lee, Hyi Seung(이희승); Lee, Yeon Ju(이연주); Lee, Jong Seok(이종석); Shin, Hee Jae(신희재)
- Alternative Author(s)
- TAREQ; 이민아; 이희승; 이연주; 이종석; 신희재
- Publication Year
- 2014-02-07
- Abstract
- Gageotetrins A-C (1-3), a unique class of linear lipopeptides, consisting of di- and tetrapeptides and a new fatty acid were isolated from a Marine Bacillus subtilis. The structures of 1-3 were assigned by spectroscopic data and their absolute stereochemistries were ascertained by chemical derivatization. Compounds 1-3 displayed good antimicrobial activities with MIC values of 0.01-0.06 mu M. However, these compounds failed to register any cytotoxicity (GI(50) > 30 mu g/ml) against human cancer cell lines.
- ISSN
- 1523-7060
- Bibliographic Citation
- ORGANIC LETTERS, v.16, no.3, pp.928 - 931, 2014
- Publisher
- AMER CHEMICAL SOC
- Subject
- PHYTOPHTHORA-CAPSICI; DIVERSITY
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
