Isolation of hypoxic stress responsive genes in a mussel (Mytilus galloprovincialis)

Title
Isolation of hypoxic stress responsive genes in a mussel (Mytilus galloprovincialis)
Author(s)
원효경; 전혜영; 김보라; 우선옥; 염승식
KIOST Author(s)
Yum, Seungshic(염승식)
Publication Year
2010-11-09
Abstract
The extensive isolation of genes responsive to hypoxic conditions in mussel (Mytilus galloprovincialis) is described. A mussel species was exposed to hypoxic condition and gene candidates whose transcript levels changed in response to hypoxic condition were identified by differential display polymerase chain reaction (DD-PCR). Sixty eight types of candidate genes were identified, 36 of which were upregulated in expression and 32 of which were downregulated. The genes were found to function in translation, ribosomal structure and biogenesis (J); replication, recombination and repair (L); defense mechanisms (V); signal transduction mechanisms (T); cytoskeleton (Z); extracellular structures (W); post-translational modification, protein turnover and chaperones (O); energy production and conversion (C); carbohydrate transport and metabolism (G); amino acid transport and metabolism (E); lipid transport and metabolism (I); inorganic ion transport and metabolism (P) and finally general function prediction only (R) based on KOG classification, though 25 of them were not applicable. These isolated gene candidates were differentially expressed and therefore have great potential as molecular biomarkers for the identification of hypoxic stressor and understanding the biological responses to hypoxia.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/28544
Bibliographic Citation
SETAC North America 31st Annual Meeting, pp.283, 2010
Publisher
Society of Environmental Chemistry and Toxicology
Type
Conference
Language
English
Publisher
Society of Environmental Chemistry and Toxicology
Related Researcher
Research Interests

Marine Genomics,Environmental Genomics,Novel biomaterials,해양생물유전체,생태환경유전체,바이오신소재

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