The transcriptional changes in Mytilus galloprovincialis by hypoxic stress

Title
The transcriptional changes in Mytilus galloprovincialis by hypoxic stress
Author(s)
우선옥; 원효경; 이애경; 염승식
KIOST Author(s)
Lee, Na Yun(이나윤)Yum, Seungshic(염승식)
Publication Year
2011-11-11
Abstract
The hypoxia caused by eutrophication is considered one of the serious threats to coastal marine ecosystems. To investigate the transcriptional responses of marine organisms exposed to oxygen depletion stress and to explore the differentially expressed genes induced or repressed by hypoxia, differential display polymerase chain reaction (DD-PCR) was used with mRNAs from the marine mussel, Mytilus galloprovincialis, under oxygen depletion and normal oxygen conditions. In total, 107 cDNA clones were differentially expressed under hypoxic conditions relative to the control mussel group. The differentially expressed genes were analyzed to determine the effects of hypoxia. They were classified into five functional categories: information storage and processing, cellular processes and signaling, metabolism, predicted general function only, and function unknown. The differentially expressed genes were predominantly associated with cellular processing and signaling, and they were particularly related to the signal transduction mechanism, posttranslational modification, and chaperone functions. The observed differences in the DD-PCR of 10 genes (encoding elongation factor 1 alpha, heat shock protein 90, calcium/calmodulin-dependent protein kinase II, GTPase-activating protein, 18S ribosomal RNA, cytochrome oxidase subunit 1, ATP synthase, chitinase, phosphoglycerate/bisphosphoglycerate mutase fa
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/28049
Bibliographic Citation
Mol. Cell. & Toxicol., pp.54, 2011
Publisher
Springer
Type
Conference
Language
English
Publisher
Springer
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