Octaphlorethol A isolated from Ishige foliacea prevents and protects against high glucose-induced oxidative damage in vitro and in vivo SCIE SCOPUS
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kang, Min-Cheol | - |
| dc.contributor.author | Kim, Kil-Nam | - |
| dc.contributor.author | Lakmal, H. H. Chaminda | - |
| dc.contributor.author | Kim, Eun-A. | - |
| dc.contributor.author | Wijesinghe, W. A. J. P. | - |
| dc.contributor.author | Yang, Xiudong | - |
| dc.contributor.author | Heo, Soo-Jin | - |
| dc.contributor.author | Jeon, You-Jin | - |
| dc.date.accessioned | 2020-04-20T04:25:44Z | - |
| dc.date.available | 2020-04-20T04:25:44Z | - |
| dc.date.created | 2020-01-28 | - |
| dc.date.issued | 2014-09 | - |
| dc.identifier.issn | 1382-6689 | - |
| dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/2729 | - |
| dc.description.abstract | We investigated the protective effect of octaphlorethol A (OPA) isolated from Ishige foliacea against high-glucose-induced oxidative damage, as indicated by reactive oxygen species (ROS) generation, lipid peroxidation, and cell death, in human umbilical vein endothelial cells (HUVECs) and in a zebrafish model. OPA treatment significantly and dose-dependently decreased ROS generation, lipid peroxidation, and cell death in HUVECs and in a zebrafish model. Our results show that OPA can protect HUVECs and zebrafish against high glucose by suppressing intracellular ROS generation, lipid peroxidation, and cell death. (C) 2014 Elsevier B.V. All rights reserved. | - |
| dc.description.uri | 1 | - |
| dc.language | English | - |
| dc.publisher | ELSEVIER | - |
| dc.subject | ECKLONIA-CAVA | - |
| dc.subject | BROWN ALGA | - |
| dc.subject | LIPID-PEROXIDATION | - |
| dc.subject | DIABETIC-PATIENTS | - |
| dc.subject | CELL-DAMAGE | - |
| dc.subject | STRESS | - |
| dc.subject | HYPERGLYCEMIA | - |
| dc.subject | ZEBRAFISH | - |
| dc.subject | COMPOUND | - |
| dc.subject | EXTRACT | - |
| dc.title | Octaphlorethol A isolated from Ishige foliacea prevents and protects against high glucose-induced oxidative damage in vitro and in vivo | - |
| dc.type | Article | - |
| dc.citation.endPage | 615 | - |
| dc.citation.startPage | 607 | - |
| dc.citation.title | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | - |
| dc.citation.volume | 38 | - |
| dc.citation.number | 2 | - |
| dc.contributor.alternativeName | 허수진 | - |
| dc.identifier.bibliographicCitation | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v.38, no.2, pp.607 - 615 | - |
| dc.identifier.doi | 10.1016/j.etap.2014.08.001 | - |
| dc.identifier.scopusid | 2-s2.0-84908396823 | - |
| dc.identifier.wosid | 000343838300029 | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | ECKLONIA-CAVA | - |
| dc.subject.keywordPlus | BROWN ALGA | - |
| dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
| dc.subject.keywordPlus | DIABETIC-PATIENTS | - |
| dc.subject.keywordPlus | CELL-DAMAGE | - |
| dc.subject.keywordPlus | STRESS | - |
| dc.subject.keywordPlus | HYPERGLYCEMIA | - |
| dc.subject.keywordPlus | ZEBRAFISH | - |
| dc.subject.keywordPlus | COMPOUND | - |
| dc.subject.keywordPlus | EXTRACT | - |
| dc.subject.keywordAuthor | High glucose | - |
| dc.subject.keywordAuthor | Octaphlorethol A | - |
| dc.subject.keywordAuthor | Oxidative stress | - |
| dc.subject.keywordAuthor | Zebrafish model | - |
| dc.subject.keywordAuthor | Hyperglycemia | - |
| dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
| dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
| dc.relation.journalWebOfScienceCategory | Toxicology | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Toxicology | - |
- Appears in Collections:
- Jeju Research Institute > Jeju Bio Research Center > 1. Journal Articles
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