INNATE IMMUNE AND BIOTRANSFORMATION RESPONSES BY FEEDING EXPOSURE TO IRANIAN HEAVY CRUDE OIL ON ROCKFISH (SEBASTES SCHLEGELI)

DC Field Value Language
dc.contributor.author 김하나 -
dc.contributor.author 정지현 -
dc.contributor.author 채영선 -
dc.contributor.author 심원준 -
dc.contributor.author 박찬일 -
dc.date.accessioned 2020-07-16T09:31:47Z -
dc.date.available 2020-07-16T09:31:47Z -
dc.date.created 2020-02-11 -
dc.date.issued 2013-05-08 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/27084 -
dc.description.abstract In the study,w e exposedju veniler ockfishto spilledc rudeo il (lranianH eavyC rudeO il IHCOi ngelatin capsulesf)r om the Hebei spirit oil spill by feeding.T he effectso n multiplef ishhepatodetoxificatioenn zymes( CytochromeP 4501Aa nd GST)a nd the expressionle vel of theimmuner esponseg enes,in cludingin terleukin-1be(tlaL -1p)g, ranulocyleco lony-stimulatifnagc tor(G-CSFa)n dC athepsiLn (CTSLw),e re measuredin the liver,s pleena nd kidneyT. heo il-fedf ishh adsignificantlhyi gherc oncentrationosf biliaryf luorescenmt etaboliteasn d CYPlAe xpressiodnu ringthe initials tagea fter exposure( L2*48h r after exposuret)h an those in the livera nd kidneyo f thecontrogl roup.S imilarlyth, e highesmt RNAe xpressiolne velso f lL-1p andG -CSwFe red etectedin thelivera t the earlys tageso f exposure(1 2h r aftere xposure)F.o llowinegx posuret,h e levelso f lSG15and G-CSFm RNAr emainedh igha t 120h r aftert reatmenti n the liverb ut the levelso f lL-l p andCTSLg raduallyd ecreasetdo an expressiolne vele qualt o or lesst hant he controlg roup.O ur datasuggestth at the innatei mmunea ndh epatodetoxificatiroens ponseisn oil-fedf ishw erei nduceda tthe initials tageo f exposureto the IHCOa t the samet ime but severailm mune-relategde nesdecreasetdo lesst hant hat of the controlg roupa ftert he initials tageo f responseT.h ec umulativemortalitiews erec alculateedv erydapy ost-bactericahl allengeA. significanint creasien fishm ortalitywas also observedi n oil exposureg roup comparedt o the sham group.T herefore,im munedisturbanceins fishe xposedto IHCOm aya llowt he pathogensin, cludintgh e infectiouds iseasesto,moree asilya ffectf ish. -
dc.description.uri 1 -
dc.language English -
dc.publisher 17th PRIMO -
dc.relation.isPartOf 17th Pollutant Responses in Marine Organisms -
dc.title INNATE IMMUNE AND BIOTRANSFORMATION RESPONSES BY FEEDING EXPOSURE TO IRANIAN HEAVY CRUDE OIL ON ROCKFISH (SEBASTES SCHLEGELI) -
dc.type Conference -
dc.citation.conferencePlace NE -
dc.citation.endPage 366 -
dc.citation.startPage 366 -
dc.citation.title 17th Pollutant Responses in Marine Organisms -
dc.contributor.alternativeName 김하나 -
dc.contributor.alternativeName 정지현 -
dc.contributor.alternativeName 채영선 -
dc.contributor.alternativeName 심원준 -
dc.identifier.bibliographicCitation 17th Pollutant Responses in Marine Organisms, pp.366 -
dc.description.journalClass 1 -
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