INNATE IMMUNE AND BIOTRANSFORMATION RESPONSES BY FEEDING EXPOSURE TO IRANIAN HEAVY CRUDE OIL ON ROCKFISH (SEBASTES SCHLEGELI)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김하나 | - |
dc.contributor.author | 정지현 | - |
dc.contributor.author | 채영선 | - |
dc.contributor.author | 심원준 | - |
dc.contributor.author | 박찬일 | - |
dc.date.accessioned | 2020-07-16T09:31:47Z | - |
dc.date.available | 2020-07-16T09:31:47Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2013-05-08 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/27084 | - |
dc.description.abstract | In the study,w e exposedju veniler ockfishto spilledc rudeo il (lranianH eavyC rudeO il IHCOi ngelatin capsulesf)r om the Hebei spirit oil spill by feeding.T he effectso n multiplef ishhepatodetoxificatioenn zymes( CytochromeP 4501Aa nd GST)a nd the expressionle vel of theimmuner esponseg enes,in cludingin terleukin-1be(tlaL -1p)g, ranulocyleco lony-stimulatifnagc tor(G-CSFa)n dC athepsiLn (CTSLw),e re measuredin the liver,s pleena nd kidneyT. heo il-fedf ishh adsignificantlhyi gherc oncentrationosf biliaryf luorescenmt etaboliteasn d CYPlAe xpressiodnu ringthe initials tagea fter exposure( L2*48h r after exposuret)h an those in the livera nd kidneyo f thecontrogl roup.S imilarlyth, e highesmt RNAe xpressiolne velso f lL-1p andG -CSwFe red etectedin thelivera t the earlys tageso f exposure(1 2h r aftere xposure)F.o llowinegx posuret,h e levelso f lSG15and G-CSFm RNAr emainedh igha t 120h r aftert reatmenti n the liverb ut the levelso f lL-l p andCTSLg raduallyd ecreasetdo an expressiolne vele qualt o or lesst hant he controlg roup.O ur datasuggestth at the innatei mmunea ndh epatodetoxificatiroens ponseisn oil-fedf ishw erei nduceda tthe initials tageo f exposureto the IHCOa t the samet ime but severailm mune-relategde nesdecreasetdo lesst hant hat of the controlg roupa ftert he initials tageo f responseT.h ec umulativemortalitiews erec alculateedv erydapy ost-bactericahl allengeA. significanint creasien fishm ortalitywas also observedi n oil exposureg roup comparedt o the sham group.T herefore,im munedisturbanceins fishe xposedto IHCOm aya llowt he pathogensin, cludintgh e infectiouds iseasesto,moree asilya ffectf ish. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | 17th PRIMO | - |
dc.relation.isPartOf | 17th Pollutant Responses in Marine Organisms | - |
dc.title | INNATE IMMUNE AND BIOTRANSFORMATION RESPONSES BY FEEDING EXPOSURE TO IRANIAN HEAVY CRUDE OIL ON ROCKFISH (SEBASTES SCHLEGELI) | - |
dc.type | Conference | - |
dc.citation.conferencePlace | NE | - |
dc.citation.endPage | 366 | - |
dc.citation.startPage | 366 | - |
dc.citation.title | 17th Pollutant Responses in Marine Organisms | - |
dc.contributor.alternativeName | 김하나 | - |
dc.contributor.alternativeName | 정지현 | - |
dc.contributor.alternativeName | 채영선 | - |
dc.contributor.alternativeName | 심원준 | - |
dc.identifier.bibliographicCitation | 17th Pollutant Responses in Marine Organisms, pp.366 | - |
dc.description.journalClass | 1 | - |