Cytotoxic Sesterterpenoids Isolated from the Marine Sponge Scalarispongia sp. SCIE SCOPUS
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- Title
- Cytotoxic Sesterterpenoids Isolated from the Marine Sponge Scalarispongia sp.
- KIOST Author(s)
- Lee, Yeon Ju(이연주); Lee, Hyi Seung(이희승)
- Alternative Author(s)
- 이연주; 이정우; 이동근; 이희승
- Publication Year
- 2014-11
- Abstract
- Eight scalarane sesterterpenoids, including four new compounds, were isolated from the marine sponge Scalarispongia sp. The structures of the new compounds were elucidated by 2D-NMR and HRMS analyses. All of the isolated compounds, with the exception of 16-O-deacetyl-12,16-epi-scalarolbutanolide, showed significant in vitro cytotoxicity (GI50 values down to 5.2 mu M) against six human cancer cell lines.
- ISSN
- 1422-0067
- Bibliographic Citation
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.15, no.11, pp.20045 - 20053, 2014
- Publisher
- MDPI
- Keywords
- sponge; Scalarispongia; sesterterpenoid; scalarane; cytotoxicity
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
