New Derivatives of Natural Acyclic Guanidine Alkaloids with TRPV Receptor-Regulating Properties SCIE SCOPUS

DC Field Value Language
dc.contributor.author Ogurtsova, Ekaterina K. -
dc.contributor.author Makarieva, Tatyana N. -
dc.contributor.author Korolkova, Yuliya V. -
dc.contributor.author Andreev, Yaroslav A. -
dc.contributor.author Mosharova, Irina V. -
dc.contributor.author Denisenko, Vladimir A. -
dc.contributor.author Dmitrenok, Pavel S. -
dc.contributor.author Lee, Yeon-Ju -
dc.contributor.author Grishin, Eugene V. -
dc.contributor.author Stonik, Valentin A. -
dc.date.accessioned 2020-04-20T03:25:58Z -
dc.date.available 2020-04-20T03:25:58Z -
dc.date.created 2020-01-28 -
dc.date.issued 2015-07 -
dc.identifier.issn 1934-578X -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/2450 -
dc.description.abstract The guanidine alkaloids, dihydropulchranin A (2), prepared from pulchranin A from the sponge Monanchora pulchra and hexadecylguanidine (3), a synthetic analog of pulchranins, were studied for their TRPV channel-regulating activities. Compound 2 was active as an inhibitor of rTRPV1 and hTRPV3 receptors with EC50 values of 24.3 and 59.1 mu M, respectively. Hexadecylguanidine (3) was not active against these receptors. -
dc.description.uri 1 -
dc.language English -
dc.publisher NATURAL PRODUCTS INC -
dc.subject SPONGE MONANCHORA-PULCHRA -
dc.subject EASTERN MARINE SPONGE -
dc.subject CHEMISTRY -
dc.subject PRODUCTS -
dc.subject CHANNELS -
dc.subject BIOLOGY -
dc.title New Derivatives of Natural Acyclic Guanidine Alkaloids with TRPV Receptor-Regulating Properties -
dc.type Article -
dc.citation.endPage 1173 -
dc.citation.startPage 1171 -
dc.citation.title NATURAL PRODUCT COMMUNICATIONS -
dc.citation.volume 10 -
dc.citation.number 7 -
dc.contributor.alternativeName 이연주 -
dc.identifier.bibliographicCitation NATURAL PRODUCT COMMUNICATIONS, v.10, no.7, pp.1171 - 1173 -
dc.identifier.scopusid 2-s2.0-84946908024 -
dc.identifier.wosid 000359095700008 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus SPONGE MONANCHORA-PULCHRA -
dc.subject.keywordPlus EASTERN MARINE SPONGE -
dc.subject.keywordPlus CHEMISTRY -
dc.subject.keywordPlus PRODUCTS -
dc.subject.keywordPlus CHANNELS -
dc.subject.keywordPlus BIOLOGY -
dc.subject.keywordAuthor Acyclic guanidine alkaloids -
dc.subject.keywordAuthor Structure-activity relationships -
dc.subject.keywordAuthor Sponge -
dc.subject.keywordAuthor Monanchora pulchra -
dc.subject.keywordAuthor rTRPV1 -
dc.subject.keywordAuthor hTRPV3 -
dc.subject.keywordAuthor rTRPA1 -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Food Science & Technology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
dc.relation.journalResearchArea Food Science & Technology -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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