New Derivatives of Natural Acyclic Guanidine Alkaloids with TRPV Receptor-Regulating Properties SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Ogurtsova, Ekaterina K. | - |
dc.contributor.author | Makarieva, Tatyana N. | - |
dc.contributor.author | Korolkova, Yuliya V. | - |
dc.contributor.author | Andreev, Yaroslav A. | - |
dc.contributor.author | Mosharova, Irina V. | - |
dc.contributor.author | Denisenko, Vladimir A. | - |
dc.contributor.author | Dmitrenok, Pavel S. | - |
dc.contributor.author | Lee, Yeon-Ju | - |
dc.contributor.author | Grishin, Eugene V. | - |
dc.contributor.author | Stonik, Valentin A. | - |
dc.date.accessioned | 2020-04-20T03:25:58Z | - |
dc.date.available | 2020-04-20T03:25:58Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2015-07 | - |
dc.identifier.issn | 1934-578X | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/2450 | - |
dc.description.abstract | The guanidine alkaloids, dihydropulchranin A (2), prepared from pulchranin A from the sponge Monanchora pulchra and hexadecylguanidine (3), a synthetic analog of pulchranins, were studied for their TRPV channel-regulating activities. Compound 2 was active as an inhibitor of rTRPV1 and hTRPV3 receptors with EC50 values of 24.3 and 59.1 mu M, respectively. Hexadecylguanidine (3) was not active against these receptors. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | NATURAL PRODUCTS INC | - |
dc.subject | SPONGE MONANCHORA-PULCHRA | - |
dc.subject | EASTERN MARINE SPONGE | - |
dc.subject | CHEMISTRY | - |
dc.subject | PRODUCTS | - |
dc.subject | CHANNELS | - |
dc.subject | BIOLOGY | - |
dc.title | New Derivatives of Natural Acyclic Guanidine Alkaloids with TRPV Receptor-Regulating Properties | - |
dc.type | Article | - |
dc.citation.endPage | 1173 | - |
dc.citation.startPage | 1171 | - |
dc.citation.title | NATURAL PRODUCT COMMUNICATIONS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 7 | - |
dc.contributor.alternativeName | 이연주 | - |
dc.identifier.bibliographicCitation | NATURAL PRODUCT COMMUNICATIONS, v.10, no.7, pp.1171 - 1173 | - |
dc.identifier.scopusid | 2-s2.0-84946908024 | - |
dc.identifier.wosid | 000359095700008 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | SPONGE MONANCHORA-PULCHRA | - |
dc.subject.keywordPlus | EASTERN MARINE SPONGE | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.subject.keywordPlus | PRODUCTS | - |
dc.subject.keywordPlus | CHANNELS | - |
dc.subject.keywordPlus | BIOLOGY | - |
dc.subject.keywordAuthor | Acyclic guanidine alkaloids | - |
dc.subject.keywordAuthor | Structure-activity relationships | - |
dc.subject.keywordAuthor | Sponge | - |
dc.subject.keywordAuthor | Monanchora pulchra | - |
dc.subject.keywordAuthor | rTRPV1 | - |
dc.subject.keywordAuthor | hTRPV3 | - |
dc.subject.keywordAuthor | rTRPA1 | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |