Differentially expressed genes in endocrine disrupting chemicals exposed marine medaka

Title
Differentially expressed genes in endocrine disrupting chemicals exposed marine medaka
Author(s)
조예진; 이나영; 이나윤; 염승식
KIOST Author(s)
Jo, Yejin(조예진)Lee, Na Yun(이나윤)Yum, Seungshic(염승식)
Publication Year
2016-11-10
Abstract
The differentially expressed genes in the liver tissue of the marine medaka fish, Oryzias javanicus, were profiled using an oligo-microarray (EnviHaz-Fish Array) which contains oligonucleotide probes for 22,796 unigenes of O. javanicus, after the fish were exposed to five kinds of endocrine disrupting chemicals (EDCs), bisphenol A (BPA), 17β-estradiol (E2), nonylphenol (NP), perfluorooctanesulfonate (PFOS), and triclosan (TCS) for 12, 24, 48, or 72 h to predict the metabolic and physiological changes with exposure time. The transcriptomic changes were highly dynamic in the EDC-exposed fish groups by the exposure time. The differentially expressed genes were used to predict the changes that occurred in the metabolic pathways and processes in response to EDCs exposure.er the fish were exposed to five kinds of endocrine disrupting chemicals (EDCs), bisphenol A (BPA), 17β-estradiol (E2), nonylphenol (NP), perfluorooctanesulfonate (PFOS), and triclosan (TCS) for 12, 24, 48, or 72 h to predict the metabolic and physiological changes with exposure time. The transcriptomic changes were highly dynamic in the EDC-exposed fish groups by the exposure time. The differentially expressed genes were used to predict the changes that occurred in the metabolic pathways and processes in response to EDCs exposure.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/24341
Bibliographic Citation
2016 대한독성유전단백체학회, pp.140, 2016
Publisher
2016
Type
Conference
Language
English
Publisher
2016
Related Researcher
Files in This Item:
There are no files associated with this item.

qrcode

Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse