De Novo Assembly of the Jellyfish, Nemopilema nomurai Genome

Title
De Novo Assembly of the Jellyfish, Nemopilema nomurai Genome
Author(s)
염승식
KIOST Author(s)
Yum, Seungshic(염승식)
Publication Year
2017-12-12
Abstract
We have successfully generated and assembled a draft genome sequence of the giant jellyfish, Nemopilema nomurai using PacBio RS long-read sequencing technology. Approximately 213-megabase genome of the jellyfish showed very high heterozyogocity. The assembly results showed that the N50 was 2,711,397 bases and the longest contig reached to 8,511,441 bases. A total of 18,528 high-quality protein-coding genes were predicted from 255 assembled scaffolds. The genome of N. nomurai showed expanded gene families in neurotransmitter transport and metallopeptidase activities, and contracted gene families in nucleosome and chromatin organization. GO enrichment test of the genes involved in the expanded gene families showed the terms of neuron differentiation and regulation of neurogenesis. Also, these genes were significantly enriched in Regulation of actin cytoskeleton pathway by KEGG pathway annotation. The jellyfish genome will also provide us some clues on the molecular regulation of the scyphozoan metamorphosis.city. The assembly results showed that the N50 was 2,711,397 bases and the longest contig reached to 8,511,441 bases. A total of 18,528 high-quality protein-coding genes were predicted from 255 assembled scaffolds. The genome of N. nomurai showed expanded gene families in neurotransmitter transport and metallopeptidase activities, and contracted gene families in nucleosome and chromatin organization. GO enrichment test of the genes involved in the expanded gene families showed the terms of neuron differentiation and regulation of neurogenesis. Also, these genes were significantly enriched in Regulation of actin cytoskeleton pathway by KEGG pathway annotation. The jellyfish genome will also provide us some clues on the molecular regulation of the scyphozoan metamorphosis.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/23519
Bibliographic Citation
International Conference Celebrating the 10th anniversary of KoEHS, pp.s25, 2017
Publisher
대한환경위해성보건과학회
Type
Conference
Language
English
Publisher
대한환경위해성보건과학회
Related Researcher
Research Interests

Marine Genomics,Environmental Genomics,Novel biomaterials,해양생물유전체,생태환경유전체,바이오신소재

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