Bioactive compounds from a marine yeast Cystobasidium benthicum isolated from deep-sea sediment

Title
Bioactive compounds from a marine yeast Cystobasidium benthicum isolated from deep-sea sediment
Author(s)
이화선; 이희승; 이종석; 이연주; 이지훈; 신희재
KIOST Author(s)
Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)Lee, Yeon Ju(이연주)Lee, Jihoon(이지훈)
Publication Year
2018-09-11
Abstract
Natural products and their derivatives have been recognized as a attractive source of drug discovery.1 In particular, microorganisms from the marine environment, a rich source of structurally unique bioactive metabolites, have produced a number of drug candidates.2 Among them, marine microbes from the deep-sea are relatively untapped reservoir of unique structural and biological diversity waiting to be discovered because of lack of technology and difficult to collect.3 In our continuing search for bioactive substances from deep-sea microorganisms, we encountered a marine-derived yeast Cystobasidium benthicum. This strain was isolated from a deep-sea sediment sample collected by a multicorer in the Indian Ocean in August, 2017. We report here the isolation of bioactive compounds from the ethyl acetate extract of culture broth of C. benthicum by chromatographic methods along with their structure determination by analysis of spectoscopic data.mber of drug candidates.2 Among them, marine microbes from the deep-sea are relatively untapped reservoir of unique structural and biological diversity waiting to be discovered because of lack of technology and difficult to collect.3 In our continuing search for bioactive substances from deep-sea microorganisms, we encountered a marine-derived yeast Cystobasidium benthicum. This strain was isolated from a deep-sea sediment sample collected by a multicorer in the Indian Ocean in August, 2017. We report here the isolation of bioactive compounds from the ethyl acetate extract of culture broth of C. benthicum by chromatographic methods along with their structure determination by analysis of spectoscopic data.
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/23146
Bibliographic Citation
15th Deep-Sea Biology Symposium, pp.65, 2018
Publisher
15th
Type
Conference
Language
English
Publisher
15th
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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