Callyazepin and (3R)-Methylazacyclodecane, Nitrogenous Macrocycles from a Callyspongia sp Sponge SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Kim, Chang-Kwon | - |
dc.contributor.author | Woo, Jung-Kyun | - |
dc.contributor.author | Lee, Yeon-Ju | - |
dc.contributor.author | Lee, Hyi-Seung | - |
dc.contributor.author | Sim, Chung J. | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.contributor.author | Oh, Ki-Bong | - |
dc.contributor.author | Shin, Jongheon | - |
dc.date.accessioned | 2020-04-20T02:40:18Z | - |
dc.date.available | 2020-04-20T02:40:18Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/2207 | - |
dc.description.abstract | Callyazepin (1) and (3R)-methylazacyclodecane (2), nitrogenous macrocycles, were isolated from a tropical Callyspongia sp. sponge. The combined spectroscopic analyses revealed that the structure of 1 is a bicyclic azepane ammonium salt of a novel structural class derived from mixed biogenetic origins. The configuration of the whole molecule and the conformation of the formamide group were assigned by proton-proton coupling constants, a NOESY analysis, and the application of the phenylglycine methyl ester method. The structure of 2 was identified using combined spectroscopic analyses and ECD measurements. These compounds exhibited moderate cytotoxic activities against the K562 and A549 cell lines. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | MARINE NATURAL-PRODUCTS | - |
dc.subject | ABSOLUTE-CONFIGURATION | - |
dc.subject | HALICLONA-TULEARENSIS | - |
dc.subject | CIRCULAR-DICHROISM | - |
dc.subject | DNP DERIVATIVES | - |
dc.subject | RENIERA-SARAI | - |
dc.subject | AMINO-ACIDS | - |
dc.subject | HALICLORENSIN | - |
dc.subject | METABOLITES | - |
dc.subject | HALITULIN | - |
dc.title | Callyazepin and (3R)-Methylazacyclodecane, Nitrogenous Macrocycles from a Callyspongia sp Sponge | - |
dc.type | Article | - |
dc.citation.endPage | 1183 | - |
dc.citation.startPage | 1179 | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 79 | - |
dc.citation.number | 4 | - |
dc.contributor.alternativeName | 이연주 | - |
dc.contributor.alternativeName | 이희승 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.79, no.4, pp.1179 - 1183 | - |
dc.identifier.doi | 10.1021/acs.jnatprod.5b01078 | - |
dc.identifier.scopusid | 2-s2.0-84967319397 | - |
dc.identifier.wosid | 000374915800066 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | MARINE NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | ABSOLUTE-CONFIGURATION | - |
dc.subject.keywordPlus | HALICLONA-TULEARENSIS | - |
dc.subject.keywordPlus | CIRCULAR-DICHROISM | - |
dc.subject.keywordPlus | DNP DERIVATIVES | - |
dc.subject.keywordPlus | RENIERA-SARAI | - |
dc.subject.keywordPlus | AMINO-ACIDS | - |
dc.subject.keywordPlus | HALICLORENSIN | - |
dc.subject.keywordPlus | METABOLITES | - |
dc.subject.keywordPlus | HALITULIN | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |