Synthesis and algicidal activity of new dichlorobenzylamine derivatives against harmful red tides SCIE SCOPUS KCI

Cited 3 time in WEB OF SCIENCE Cited 3 time in Scopus
Title
Synthesis and algicidal activity of new dichlorobenzylamine derivatives against harmful red tides
Author(s)
Choi, Dubok; Yu, Sunjong; Baek, Seung Ho; Kang, Yoon-Ho; Chang, Young-Cheol; Cho, Hoon
KIOST Author(s)
Baek, Seung Ho(백승호)
Publication Year
2016-06
Abstract
In the present study, we synthesized 65 dichlorobenzylamine derivatives and investigated their algicidal activity against harmful red tides. The 3,4-dichlorobenzylamine derivatives showed relatively high activity against Cochlodinium polykrikoides, Heterosigma akashiwo, Chattonella marina, and Heterocapsa circularisquama, and the synthesized compounds 27, 28, 33, 34, 35, and 36 showed the highest algicidal activity after 24 h at 0.1 similar to 1.0 mu M LC50 against the four harmful algae species. To verify the safety of the compounds, acute ecotoxicology tests using the water flea (Daphnia magna) and zebrafish (Danio rerio) were conducted, and the tests confirmed that compounds 33 and 34 were not harmful because the target organisms showed high survival rates at 15 mu M. The results indicate that compounds 33 and 34 are suitable substances for use in controlling harmful algae species.
ISSN
1226-8372
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/2190
DOI
10.1007/s12257-016-0175-8
Bibliographic Citation
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.3, pp.463 - 476, 2016
Publisher
KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING
Subject
STRAW HORDEUM-VULGARE; THIAZOLIDINEDIONE DERIVATIVES; CLAY FLOCCULATION; ALGAL BLOOMS; REMOVAL; CULTURE
Keywords
harmful algae blooms; algicides; red tide; dichlorobenzylamine; ecotoxicology
Type
Article
Language
English
Document Type
Article
Publisher
KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING
Related Researcher
Research Interests

Marine Ecology,Marine Environment,HABs,해양생태,해양환경,적조

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