유전자변형 어류의 과학적 배경:초기 연구, 획기적인 연구 결과 그리고 향후 전망

Abstract

A. Generation of sterile transgenic triploid stock : By blocking the second meiosis (extrusion of the 2nd polar body) : Retarded gonad development : Minimizing the risk associated with unwanted reproduction of accidentally released transgenic fishB. Establishment of transgenic homozygous line : By parthenogenetic reproduction (exclusive doubling of maternal or paternal genome) : Facilitated transmission of transgene with increasing yield : Clonal population by successive artificial parthenogenesisC. Generation of sterile transgenic triploid hybrid stock : By interspecific hybridization with cyprinid loach followed by triploidization : Complete removal of reproductive capacity of transgenic fish : Desirable morphology in hybrid genotype