Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties
SCIE
SCOPUS
Cited 57 time in
WEB OF SCIENCE
Cited 61 time in
Scopus
-
Title
- Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties
-
Author(s)
- Mondol, Muhammad Abdul Mojid; Shin, Hee Jae; Rahman, M. Aminur; Islam, Mohamad Tofazzal
- KIOST Author(s)
- Shin, Hee Jae(신희재)
-
Alternative Author(s)
- 신희재
-
Publication Year
- 2017-10
-
Abstract
- Sea cucumbers belonging to echinoderm are traditionally used as tonic food in China and other Asian countries. They produce abundant biologically active triterpene glycosides. More than 300 triterpene glycosides have been isolated and characterized from various species of sea cucumbers, which are classified as holostane and nonholostane depending on the presence or absence of a specific structural unit (18,20)-lactone in the aglycone. Triterpene glycosides contain a carbohydrate chain up to six monosaccharide units mainly consisting of d-xylose, 3-O-methy-d-xylose, d-glucose, 3-O-methyl-d-glucose, and d-quinovose. Cytotoxicity is the common biological property of triterpene glycosides isolated from sea cucumbers. Besides cytotoxicity, triterpene glycosides also exhibit antifungal, antiviral and hemolytic activities. This review updates and summarizes our understanding on diverse chemical structures of triterpene glycosides from various species of sea cucumbers and their important biological activities. Mechanisms of action and structural-activity relationships (SARs) of sea cucumber glycosides are also discussed briefly.
-
ISSN
- 1660-3397
-
URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/1149
-
DOI
- 10.3390/md15100317
-
Bibliographic Citation
- MARINE DRUGS, v.15, no.10, 2017
-
Publisher
- MDPI
-
Subject
- CYTOTOXIC TRITERPENE GLYCOSIDES; EUPENTACTA FRAUDATRIX. STRUCTURE; MINOR NONSULFATED TETRAOSIDES; MARINE NATURAL-PRODUCTS; CUCUMARIA-FRONDOSA; ANTIFUNGAL OLIGOGLYCOSIDES; STAUROCUCUMIS LIOUVILLEI; PENTAMERA-CALCIGERA; COLOCHIRUS-ROBUSTUS; SAPONINS
-
Keywords
- holostane; nonholostane; cucumarioside; cytotoxic; antifungal; glycosides
-
Type
- Article
-
Language
- English
-
Document Type
- Review
- Files in This Item:
-
There are no files associated with this item.
Items in ScienceWatch@KIOST are protected by copyright, with all rights reserved, unless otherwise indicated.