Indole Alkaloids from Tropical Sponge Hyrtios sp as Isocitrate Lyase Inhibitors SCIE SCOPUS

DC Field Value Language
dc.contributor.author Park, Seung-Il -
dc.contributor.author Lee, Yeon-Ju -
dc.contributor.author Won, Hoshik -
dc.contributor.author Oh, Ki-Bong -
dc.contributor.author Lee, Hyi-Seung -
dc.date.accessioned 2020-04-16T08:55:07Z -
dc.date.available 2020-04-16T08:55:07Z -
dc.date.created 2020-01-28 -
dc.date.issued 2018-06 -
dc.identifier.issn 1934-578X -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/890 -
dc.description.abstract A new beta-carboline alkaloid, 3,4-dihydrohyrtiosulawesine (8), and fifteen known alkaloids were isolated from the tropical marine sponge Hyrtios sp. Among these known compounds, beta-ketoserotonin (10) has been isolated for the first time from a natural source. The structures of the isolated compounds were determined by spectroscopic analyses and comparison with literature values. Compound 8 displayed potent inhibitory activities against isocitrate lyase (IC50: 92.9 mu M) from Candida albicans. -
dc.description.uri 1 -
dc.language English -
dc.publisher NATURAL PRODUCTS INC -
dc.subject MARINE SPONGES -
dc.subject GLYOXYLATE CYCLE -
dc.subject BETA-CARBOLINES -
dc.subject ERECTUS -
dc.title Indole Alkaloids from Tropical Sponge Hyrtios sp as Isocitrate Lyase Inhibitors -
dc.type Article -
dc.citation.endPage 685 -
dc.citation.startPage 683 -
dc.citation.title NATURAL PRODUCT COMMUNICATIONS -
dc.citation.volume 13 -
dc.citation.number 6 -
dc.contributor.alternativeName 박승일 -
dc.contributor.alternativeName 이연주 -
dc.contributor.alternativeName 이희승 -
dc.identifier.bibliographicCitation NATURAL PRODUCT COMMUNICATIONS, v.13, no.6, pp.683 - 685 -
dc.identifier.scopusid 2-s2.0-85048994458 -
dc.identifier.wosid 000436892800008 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus MARINE SPONGES -
dc.subject.keywordPlus GLYOXYLATE CYCLE -
dc.subject.keywordPlus BETA-CARBOLINES -
dc.subject.keywordPlus ERECTUS -
dc.subject.keywordAuthor Hyrtios sp. -
dc.subject.keywordAuthor beta-Carboline alkaloids -
dc.subject.keywordAuthor Isocitrate lyase -
dc.relation.journalWebOfScienceCategory Chemistry, Medicinal -
dc.relation.journalWebOfScienceCategory Food Science & Technology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Pharmacology & Pharmacy -
dc.relation.journalResearchArea Food Science & Technology -
Appears in Collections:
Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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