Streptoglycerides A-D with a Rare 6/5/5 Tricyclic Ring Skeleton from a Marine Actinomycete Streptomyces species SCIE SCOPUS
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- Title
- Streptoglycerides A-D with a Rare 6/5/5 Tricyclic Ring Skeleton from a Marine Actinomycete Streptomyces species
- KIOST Author(s)
- Lee, Hwa Sun(이화선); Lee, Hyi Seung(이희승); Lee, Yeon Ju(이연주); Lee, Jong Seok(이종석); Lee, Ji Hoon(이지훈); Shin, Hee Jae(신희재)
- Alternative Author(s)
- 최병규; 이화선; 이희승; 이연주; 이종석; 이지훈; 신희재
- Publication Year
- 2018-10-05
- Abstract
- Four novel secondary metabolites possessing a unique 6/5/5 tricyclic ring system, streptoglycerides A-D (1-4), were isolated from a marine actinomycete Streptomyces sp. derived from a mangrove sample collected on Kosrae Island. Their structures and absolute configurations were elucidated by spectroscopic data and electronic circular dichroism data. Streptoglyceride C (3) showed a weak inhibitory effect on the production of nitric oxide in BV-2 microglia cells.
- ISSN
- 1523-7060
- Bibliographic Citation
- ORGANIC LETTERS, v.20, no.19, pp.6037 - 6040, 2018
- Publisher
- AMER CHEMICAL SOC
- Subject
- NATURAL-PRODUCTS; MICROGLIA
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
