Streptoglycerides A-D with a Rare 6/5/5 Tricyclic Ring Skeleton from a Marine Actinomycete Streptomyces species SCIE SCOPUS

Cited 6 time in WEB OF SCIENCE Cited 6 time in Scopus
Title
Streptoglycerides A-D with a Rare 6/5/5 Tricyclic Ring Skeleton from a Marine Actinomycete Streptomyces species
Author(s)
Choi, Byeoung-Kyu; Park, Shin-Young; Choi, Dong-Kug; Shin, Bora; Shin, Yern-Hyerk; Oh, Dong-Chan; Lee, Hwa-Sun; Lee, Hyi-Seung; Lee, Yeon-Ju; Lee, Jong Seok; Lee, Ji Hoon; Shin, Hee Jae
KIOST Author(s)
Choi, Byeoung Kyu(최병규)Lee, Hwa Sun(이화선)Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)Lee, Jong Soo(이종수)Lee, Jihoon(이지훈)
Publication Year
2018-10-05
Abstract
Four novel secondary metabolites possessing a unique 6/5/5 tricyclic ring system, streptoglycerides A-D (1-4), were isolated from a marine actinomycete Streptomyces sp. derived from a mangrove sample collected on Kosrae Island. Their structures and absolute configurations were elucidated by spectroscopic data and electronic circular dichroism data. Streptoglyceride C (3) showed a weak inhibitory effect on the production of nitric oxide in BV-2 microglia cells.
ISSN
1523-7060
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/817
DOI
10.1021/acs.orglett.8b02411
Bibliographic Citation
ORGANIC LETTERS, v.20, no.19, pp.6037 - 6040, 2018
Publisher
AMER CHEMICAL SOC
Subject
NATURAL-PRODUCTS; MICROGLIA
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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