Bromopyrrole Alkaloids from the Sponge Agelas kosrae SCIE SCOPUS
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kwon, Oh-Seok | - |
| dc.contributor.author | Kim, Donghwa | - |
| dc.contributor.author | Kim, Heegyu | - |
| dc.contributor.author | Lee, Yeon-Ju | - |
| dc.contributor.author | Lee, Hyi-Seung | - |
| dc.contributor.author | Sim, Chung J. | - |
| dc.contributor.author | Oh, Dong-Chan | - |
| dc.contributor.author | Lee, Sang Kook | - |
| dc.contributor.author | Oh, Ki-Bong | - |
| dc.contributor.author | Shin, Jongheon | - |
| dc.date.accessioned | 2020-04-16T08:40:04Z | - |
| dc.date.available | 2020-04-16T08:40:04Z | - |
| dc.date.created | 2020-01-28 | - |
| dc.date.issued | 2018-12 | - |
| dc.identifier.issn | 1660-3397 | - |
| dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/794 | - |
| dc.description.abstract | Two new sceptrin derivatives (1,2) and eight structurally-related known bromopyrrole-bearing alkaloids were isolated from the tropical sponge Agelas kosrae. By a combination of spectroscopic methods, the new compounds, designated dioxysceptrin (1) and ageleste C (2), were determined to be structural analogs of each other that differ at the imidazole moiety. Dioxysceptrin was also found to exist as a mixture of -amido epimers. The sceptrin alkaloids exhibited weak cytotoxicity against cancer cells. Compounds 1 and 2 also moderately exhibited anti-angiogenic and isocitrate lyase-inhibitory activities, respectively. | - |
| dc.description.uri | 1 | - |
| dc.language | English | - |
| dc.publisher | MDPI | - |
| dc.subject | MARINE | - |
| dc.subject | METABOLITES | - |
| dc.subject | HANISHIN | - |
| dc.subject | SCEPTRIN | - |
| dc.subject | OROIDIN | - |
| dc.title | Bromopyrrole Alkaloids from the Sponge Agelas kosrae | - |
| dc.type | Article | - |
| dc.citation.title | MARINE DRUGS | - |
| dc.citation.volume | 16 | - |
| dc.citation.number | 12 | - |
| dc.contributor.alternativeName | 이연주 | - |
| dc.contributor.alternativeName | 이희승 | - |
| dc.identifier.bibliographicCitation | MARINE DRUGS, v.16, no.12 | - |
| dc.identifier.doi | 10.3390/md16120513 | - |
| dc.identifier.scopusid | 2-s2.0-85058813532 | - |
| dc.identifier.wosid | 000454726400054 | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | MARINE | - |
| dc.subject.keywordPlus | METABOLITES | - |
| dc.subject.keywordPlus | HANISHIN | - |
| dc.subject.keywordPlus | SCEPTRIN | - |
| dc.subject.keywordPlus | OROIDIN | - |
| dc.subject.keywordAuthor | sceptrin | - |
| dc.subject.keywordAuthor | pyrrole-imidazole alkaloids | - |
| dc.subject.keywordAuthor | marine sponge | - |
| dc.subject.keywordAuthor | anti-angiogenesis | - |
| dc.subject.keywordAuthor | isocitrate lyase | - |
| dc.subject.keywordAuthor | bioactive marine natural products | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
- Appears in Collections:
- Marine Resources & Environment Research Division > Marine Biotechnology &Bioresource Research Department > 1. Journal Articles
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