Anti-melanogenesis activity of Ecklonia cava extract cultured in tanks with magma seawater of Jeju Island SCIE SCOPUS KCI

DC Field Value Language
dc.contributor.author Ding, Yuling -
dc.contributor.author Kim, So Hui -
dc.contributor.author Lee, Jeong Jun -
dc.contributor.author Hong, Jin Tae -
dc.contributor.author Kim, Eun-A -
dc.contributor.author Kang, Do-Hyung -
dc.contributor.author Heo, Soo-Tin -
dc.contributor.author Lee, Seung-Hong -
dc.date.accessioned 2020-04-16T08:15:05Z -
dc.date.available 2020-04-16T08:15:05Z -
dc.date.created 2020-02-04 -
dc.date.issued 2019-06 -
dc.identifier.issn 1226-2617 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/618 -
dc.description.abstract Ecklonia cava is popular in Korea as a marine functional materials. E. cava is generally collected and used on the coast of Jeju Island. however, the continuous use of collected natural E cava may be limited because difficult to secure throughout the year and may be exposed to environmental pollution. Jeju magma seawater (MSW) was known to be significant advantages such as safety, cleanness, stability, and functional improvement. Attempts have been reported on application of MSW to the culturing of macro- and microalgae and showed improved results. Thus, the objective of the present study was to explore the anti-melanogenesis activity of brown seaweed E. cava (E. cava cultured with MSW [MSWE]) extract cultured in tanks with MSW of Jeju Island to evaluate the possibility of cosmeceutical industrial application. MSWE extract showed the higher polyphenolic and dieckol contents than natural E. cava (NE) extract. Anti-melanogenesis activity of MSWE extract and NE extract are tested and compared using tyrosinase and dihydroxyphenylalanine (DOPA) oxidation inhibition assay. MSWE extracts evidenced more effective tyrosinase and DOPA oxidation inhibition activity than that of the NE extracts and the commercial whitening agent, arbutin. MSWE extracts also markedly inhibited melanin synthesis and decreased the expression of melanogenesis-related protein in alpha-melanocyte stimulating hormone-stimulated B16F10 melanoma cells without cytotoxicity. These results suggest that MSW cultivation process would be more effective in releasing bioactive compounds with whitening effect from seaweed such as E. cava at an industrial scale. -
dc.description.uri 1 -
dc.language English -
dc.publisher KOREAN SOC PHYCOLOGY -
dc.subject BROWN SEAWEEDS -
dc.subject TYROSINASE -
dc.subject FUCOXANTHIN -
dc.subject EXPRESSION -
dc.subject DOCKING -
dc.subject PROTEIN -
dc.title Anti-melanogenesis activity of Ecklonia cava extract cultured in tanks with magma seawater of Jeju Island -
dc.type Article -
dc.citation.endPage 185 -
dc.citation.startPage 177 -
dc.citation.title ALGAE -
dc.citation.volume 34 -
dc.citation.number 2 -
dc.identifier.bibliographicCitation ALGAE, v.34, no.2, pp.177 - 185 -
dc.identifier.doi 10.4490/algae.2019.34.4.30 -
dc.identifier.scopusid 2-s2.0-85069736646 -
dc.identifier.wosid 000472538200009 -
dc.type.docType Article -
dc.identifier.kciid ART002503055 -
dc.description.journalClass 1 -
dc.subject.keywordPlus BROWN SEAWEEDS -
dc.subject.keywordPlus TYROSINASE -
dc.subject.keywordPlus FUCOXANTHIN -
dc.subject.keywordPlus EXPRESSION -
dc.subject.keywordPlus DOCKING -
dc.subject.keywordPlus PROTEIN -
dc.subject.keywordAuthor anti-melanogenesis activity -
dc.subject.keywordAuthor cultivation -
dc.subject.keywordAuthor Ecklonia cava -
dc.subject.keywordAuthor Jeju magma seawater -
dc.subject.keywordAuthor polyphenolic content -
dc.relation.journalWebOfScienceCategory Plant Sciences -
dc.relation.journalWebOfScienceCategory Marine & Freshwater Biology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.description.journalRegisteredClass kci -
dc.relation.journalResearchArea Plant Sciences -
dc.relation.journalResearchArea Marine & Freshwater Biology -
Appears in Collections:
Jeju Research Institute > Jeju Marine Research Center > 1. Journal Articles
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