Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028 SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Lee, Hwa-Sun | - |
dc.contributor.author | Kang, Jong Soon | - |
dc.contributor.author | Choi, Byeoung-Kyu | - |
dc.contributor.author | Lee, Hyi-Seung | - |
dc.contributor.author | Lee, Yeon-Ju | - |
dc.contributor.author | Lee, Jihoon | - |
dc.contributor.author | Shin, Hee Jae | - |
dc.date.accessioned | 2020-04-16T07:40:17Z | - |
dc.date.available | 2020-04-16T07:40:17Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-08 | - |
dc.identifier.issn | 1660-3397 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/555 | - |
dc.description.abstract | Three new phenazine derivatives (1-3), along with known compounds (4-7) of saphenic acid derivatives, were isolated from a deep-sea sediment-derived yeast-like fungus Cystobasidium larynigs collected from the Indian Ocean. The structures of the new compounds (1-3) were determined by analysis of spectroscopic data, semi-synthesis and comparison of optical rotation values. All the isolated compounds (1-7), except for 2, showed nitric oxide (NO) production inhibitory effect against lipopolysaccharide (LPS)-induced murine macrophage RAW 264.7 cells without cytotoxicity at concentrations up to 30 mu g/mL. This is the first report on the yeast-like fungus Cystobasidium laryngis producing phenazines and anti-inflammatory activity of 1-7 including saphenic acid (4). | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.title | Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028 | - |
dc.type | Article | - |
dc.citation.title | MARINE DRUGS | - |
dc.citation.volume | 17 | - |
dc.citation.number | 8 | - |
dc.contributor.alternativeName | 이화선 | - |
dc.contributor.alternativeName | 최병규 | - |
dc.contributor.alternativeName | 이희승 | - |
dc.contributor.alternativeName | 이연주 | - |
dc.contributor.alternativeName | 이지훈 | - |
dc.contributor.alternativeName | 신희재 | - |
dc.identifier.bibliographicCitation | MARINE DRUGS, v.17, no.8 | - |
dc.identifier.doi | 10.3390/md17080482 | - |
dc.identifier.scopusid | 2-s2.0-85071318576 | - |
dc.identifier.wosid | 000484403200041 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordPlus | NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | BIOSYNTHESIS | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordAuthor | deep-sea sediment | - |
dc.subject.keywordAuthor | marine yeast-like fungi | - |
dc.subject.keywordAuthor | Cystobasidium laryngis | - |
dc.subject.keywordAuthor | phenazine derivatives | - |
dc.subject.keywordAuthor | saphenic acid | - |
dc.subject.keywordAuthor | anti-inflammatory activity | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |