Inhibition of infection of the rice blast fungus by halisulfatel 1, an isocitrate lyase inhibitor SCIE SCOPUS

Cited 11 time in WEB OF SCIENCE Cited 11 time in Scopus
Title
Inhibition of infection of the rice blast fungus by halisulfatel 1, an isocitrate lyase inhibitor
Author(s)
Shin, Dong-Sun; Lee, Tae-Hoon; Lee, Hyi-Seung; Shin, Jongheon; Oh, Ki-Bong
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2007-07
Abstract
Halisulfate 1, a sesterterpene sulfate and an isocitrate lyase (ICL) inhibitor that is isolated from tropical sponge Hippospongia spp., reduces both appressorium formation and infection of rice plants by the fungus Magnaporthe grisea. Rice plants infected with wild-type M. grisea Guy 11 exhibited significantly lower disease severity after halisulfate I treatment than without, and the treatment effect was comparable to the behavior of the Delta icl knockout mutant I-10. The protection observed upon applying halisulfate 1 to rice plants suggests that the ICL inhibitor may be a promising candidate for crop protection, particularly to protect rice plants against M. grisea.
ISSN
0378-1097
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4672
DOI
10.1111/j.1574-6968.2007.00733.x
Bibliographic Citation
FEMS MICROBIOLOGY LETTERS, v.272, no.1, pp.43 - 47, 2007
Publisher
OXFORD UNIV PRESS
Subject
MAGNAPORTHE-GRISEA; GLYOXYLATE CYCLE; PENETRATION; VIRULENCE; REQUIRES; TURGOR; ENZYME
Keywords
Magnaporthe grisea; infection; isocitrate lyase; halisulfate
Type
Article
Language
English
Document Type
Article
Publisher
OXFORD UNIV PRESS
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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