Novel monofunctional histidinol-phosphate phosphatase of the DDDD superfamily of phosphohydrolases
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Title
- Novel monofunctional histidinol-phosphate phosphatase of the DDDD superfamily of phosphohydrolases
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Author(s)
- Lee, Hyun Sook; Cho, Yona; Lee, Jung-Hyun; Kang, Sung Gyun
- KIOST Author(s)
- Lee, Hyun Sook(이현숙); Lee, Jung Hyun(이정현); Kang, Sung Gyun(강성균)
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Alternative Author(s)
- 이현숙; 조요나; 이정현; 강성균
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Publication Year
- 2008-04
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Abstract
- The TON_0887 gene was identified as the missing histidinol-phosphate phosphatase (HolPase) in the hyperthermophilic archaeon "Thermococcus onnurineus" NA1. The protein contained conserved motifs of the DDDD superfamilly of phosphohydrolase, and the recombinantly expressed protein exhibited strong HolPase activity. In this study, we functionally assessed for the first time the monofunctional DDDD-type HolPase, which is organized in the gene cluster.
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ISSN
- 0021-9193
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/4529
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DOI
- 10.1128/JB.01722-07
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Bibliographic Citation
- JOURNAL OF BACTERIOLOGY, v.190, no.7, pp.2629 - 2632, 2008
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Publisher
- AMER SOC MICROBIOLOGY
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Subject
- COMPLETE GENOME SEQUENCE; ESCHERICHIA-COLI; SACCHAROMYCES-CEREVISIAE; SALMONELLA-TYPHIMURIUM; HISB GENE; DEHYDRATASE; PATHWAY; PURIFICATION; EVOLUTION; OPERONS
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Type
- Article
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Language
- English
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Document Type
- Article
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