Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp. SCIE SCOPUS

Cited 13 time in WEB OF SCIENCE Cited 12 time in Scopus
Title
Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.
Author(s)
Lee, Hyi-Seung; Lee, Ji Hye; Won, Hoshik; Park, Song-Kyu; Kim, Hwan Mook; Shin, Hee Jae; Park, Heung Sik; Sim, Chung J.; Kim, Hye-Kyeong
KIOST Author(s)
Lee, Hyi Seung(이희승)Shin, Hee Jae(신희재)Park, Heung Sik(박흥식)
Publication Year
2009-01
Abstract
Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.
ISSN
0024-4201
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/4348
DOI
10.1007/s11745-008-3249-3
Bibliographic Citation
LIPIDS, v.44, no.1, pp.71 - 75, 2009
Publisher
WILEY
Subject
OKINAWAN MARINE SPONGE; CYTOTOXIC POLYACETYLENES; CRIBROCHALINA-VASCULUM; PETROSIA; STEREOCHEMISTRY; STRONGYLOPHORA; LIPIDS; ACID
Keywords
Tropical sponge; Reniochalina sp.; Acetylenic alcohol; Dihydrothiopyranone; Growth inhibition
Type
Article
Language
English
Document Type
Article
Publisher
WILEY
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