Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.
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Title
- Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.
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Author(s)
- Lee, Hyi-Seung; Lee, Ji Hye; Won, Hoshik; Park, Song-Kyu; Kim, Hwan Mook; Shin, Hee Jae; Park, Heung Sik; Sim, Chung J.; Kim, Hye-Kyeong
- KIOST Author(s)
- Lee, Hyi Seung(이희승); Shin, Hee Jae(신희재); Park, Heung Sik(박흥식)
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Alternative Author(s)
- 이희승; 신희재; 박흥식
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Publication Year
- 2009-01
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Abstract
- Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.
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ISSN
- 0024-4201
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/4348
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DOI
- 10.1007/s11745-008-3249-3
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Bibliographic Citation
- LIPIDS, v.44, no.1, pp.71 - 75, 2009
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Publisher
- WILEY
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Subject
- OKINAWAN MARINE SPONGE; CYTOTOXIC POLYACETYLENES; CRIBROCHALINA-VASCULUM; PETROSIA; STEREOCHEMISTRY; STRONGYLOPHORA; LIPIDS; ACID
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Keywords
- Tropical sponge; Reniochalina sp.; Acetylenic alcohol; Dihydrothiopyranone; Growth inhibition
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Type
- Article
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Language
- English
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Document Type
- Article
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