Phenotypic toxicity, oxidative response, and transcriptomic deregulation of the rotifer Brachionus plicatilis exposed to a toxic cocktail of tire-wear particle leachate SCIE SCOPUS
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Heesang | - |
dc.contributor.author | Sukumaran, Vrinda | - |
dc.contributor.author | Yeo, In-Cheol | - |
dc.contributor.author | Shim, Kyu-Young | - |
dc.contributor.author | Lee, Seokhwan | - |
dc.contributor.author | Choi, Han-Kyu | - |
dc.contributor.author | Ha, Sung Yong | - |
dc.contributor.author | Kim, Moon Koo | - |
dc.contributor.author | Jung, Jee Hyun | - |
dc.contributor.author | Lee, Jae-Seong | - |
dc.contributor.author | Jeong, Chang-Bum | - |
dc.date.accessioned | 2022-07-31T23:50:04Z | - |
dc.date.available | 2022-07-31T23:50:04Z | - |
dc.date.created | 2022-08-01 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 0304-3894 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/43111 | - |
dc.description.abstract | Tire-wear particles (TWPs) are potential source of microplastic (MP) pollution in marine environments. Although the hazardous effects of MPs on marine biota have received considerable attention, the toxicity of TWPs and associated leachates remain poorly understood. Here, to assess the toxicity of TWP leachate and the underlying mechanisms of toxicity, the phenotypic and transcriptomic responses of the rotifer Brachionus plicatilis were assessed with chemistry analysis of a TWP leachate. Although acute toxicity was induced, and a variety of metals and polyaromatic hydrocarbons were detected in the leachate, levels were below the threshold for acute toxicity. The results of particle analysis suggest that the acute toxicity observed in our study is the result of a toxic cocktail of micro- and/or nano-sized TWPs and other additives in TWP leachate. The adverse effects of TWP leachate were associated with differential expression of genes related to cellular processes, stress response, and impaired metabolism, with further oxidative stress responses. Our results imply that TWPs pose a greater threat to marine | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | Elsevier BV | - |
dc.title | Phenotypic toxicity, oxidative response, and transcriptomic deregulation of the rotifer Brachionus plicatilis exposed to a toxic cocktail of tire-wear particle leachate | - |
dc.type | Article | - |
dc.citation.startPage | 129417 | - |
dc.citation.title | Journal of Hazardous Materials | - |
dc.citation.volume | 438 | - |
dc.contributor.alternativeName | 하성용 | - |
dc.contributor.alternativeName | 김문구 | - |
dc.contributor.alternativeName | 정지현 | - |
dc.identifier.bibliographicCitation | Journal of Hazardous Materials, v.438, pp.129417 | - |
dc.identifier.doi | 10.1016/j.jhazmat.2022.129417 | - |
dc.identifier.scopusid | 2-s2.0-85137009046 | - |
dc.identifier.wosid | 000827859800003 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordPlus | BIOMARKERS | - |
dc.subject.keywordPlus | ADDITIVES | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | CARBON-BLACK PARTICLES | - |
dc.subject.keywordPlus | DAPHNIA-MAGNA | - |
dc.subject.keywordPlus | MICROPLASTICS | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | ECOTOXICOLOGY | - |
dc.subject.keywordPlus | ENVIRONMENT | - |
dc.subject.keywordAuthor | Leachate | - |
dc.subject.keywordAuthor | Microplastic | - |
dc.subject.keywordAuthor | Carbon black | - |
dc.subject.keywordAuthor | Oxidative stress | - |
dc.subject.keywordAuthor | Ecotoxicogenomics | - |
dc.relation.journalWebOfScienceCategory | Engineering, Environmental | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |