Haliclonin A, a New Macrocyclic Diamide from the Sponge Haliclona sp.
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Title
- Haliclonin A, a New Macrocyclic Diamide from the Sponge Haliclona sp.
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Author(s)
- Jang, Kyoung Hwa; Kang, Gyoung Won; Jeon, Ju-eun; Lim, Chaemin; Lee, Hyi-Seung; Sim, Chung J.; Oh, Ki-Bong; Shin, Jongheon
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
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Alternative Author(s)
- 이희승
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Publication Year
- 2009-04-16
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Abstract
- Haliclonin A (1), a macrocyclic diamide of a novel skeletal class, was isolated from the marine sponge Haliclona sp. collected from Korean waters. The structure of this compound was determined using a combination of spectroscopic and chemical analyses. The new compound exhibited moderate cytotoxicity and antibacterial activity against diverse microbial strains.
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ISSN
- 1523-7060
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/4303
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DOI
- 10.1021/ol900282m
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Bibliographic Citation
- ORGANIC LETTERS, v.11, no.8, pp.1713 - 1716, 2009
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Publisher
- AMER CHEMICAL SOC
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Subject
- MARINE SPONGE; ANTIMALARIAL ACTIVITY; POTENT ACTIVITY; TRICYCLIC CORE; MANZAMINE-B; RING-SYSTEM; SARAIN; ALKALOIDS; CONSTRUCTION; SKELETON
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Type
- Article
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Language
- English
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Document Type
- Article
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