Enantioselective total synthesis of (+)-ieodomycin A, (+)-ieodomycin B, and their three stereoisomers SCIE SCOPUS

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Title
Enantioselective total synthesis of (+)-ieodomycin A, (+)-ieodomycin B, and their three stereoisomers
Author(s)
Choi, Du-Bong; Choi, Hansol; Lee, Jihoon; Lee, Yeon Ju; Lee, Hyi Seung; Joo, Jung Min; Lee, Jong Seok
KIOST Author(s)
Lee, Ji Hoon(이지훈)Lee, Yeon Ju(이연주)Lee, Hyi Seung(이희승)Lee, Jong Seok(이종석)
Alternative Author(s)
최한솔; 이지훈; 이연주; 이희승; 이종석
Publication Year
2020-12-07
Abstract
We describe a divergent and enantioselective total synthesis of (+)-ieodomycin A and (+)-ieodomycin B with three stereoisomers. The main advantage of the present synthesis is the late-stage elaboration of the side chain, which would afford a wide range of structurally diverse analogs with interesting bioactivities.
ISSN
1477-0520
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/41380
DOI
10.1039/d0ob02107e
Bibliographic Citation
ORGANIC & BIOMOLECULAR CHEMISTRY, v.18, no.45, pp.9227 - 9230, 2020
Publisher
ROYAL SOC CHEMISTRY
Subject
STEREOSELECTIVE TOTAL-SYNTHESIS; CONCISE ASYMMETRIC-SYNTHESIS; MARINE NATURAL-PRODUCTS; DRUG DISCOVERY; IEODOMYCIN; CONSTRUCTION
Type
Article
Language
English
Document Type
Article
Publisher
ROYAL SOC CHEMISTRY
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