Antioxidant Activity of Various Solvent Fractions from Edible Brown Alga, Eisenia bicyclis and Its Active Compounds SCIE SCOPUS

Cited 27 time in WEB OF SCIENCE Cited 0 time in Scopus
Title
Antioxidant Activity of Various Solvent Fractions from Edible Brown Alga, Eisenia bicyclis and Its Active Compounds
Author(s)
Kwon, Tae-Hyung; Kim, Tae-Wan; Kim, Choong-Gon; Park, Nyun-Ho
KIOST Author(s)
Kim, Choong Gon(김충곤)
Publication Year
2013-05
Abstract
In this study, we aimed to elucidate the antioxidant capacity of Eisenia bicyclis and evaluated its antioxidant activity using various assay systems such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, 2,2-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging, reducing power ability, and content of total polyphenol. Among all the performed experiments, the ethyl acetate fraction of E. bicyclis exhibited higher antioxidant activities. From this finding, isolation and purification were performed on the ethyl acetate fraction and identified dieckol and phlorofucofureoeckol-A by spectroscopic analyses including FAB-mass in the negative mode, H-1 NMR, C-13 NMR, H-1-H-1 COSY, HMQC, and HMBC spectra. Interestingly, ABTS radical scavenging activities of dieckol and phlorofucofuroeckol showed strong effects of 65.36% and 70.38% at a concentration of 50 mu g/mL, respectively. DPPH radical scavenging and reducing power abilities were increased in a dose-dependent manner at various concentrations. These results suggest that dieckol and phlorofucofuroeckol-A of E. bicyclis may play an important role in protection from oxidative stress involving reactive oxygen species and may contribute to the development of new bio products, for example, a useful preservative to improve food quality and a drug for various oxidative damage-associated diseases.
ISSN
0022-1147
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/40430
DOI
10.1111/1750-3841.12109
Bibliographic Citation
JOURNAL OF FOOD SCIENCE, v.78, no.5, pp.C679 - C684, 2013
Publisher
WILEY
Subject
ECKLONIA-CAVA; EXTRACTS
Keywords
antioxidant activity; brown seaweed; dieckol; phlorofucofuroeckol-A; Eisenia bicyclis
Type
Article
Language
English
Document Type
Article
Publisher
WILEY
Related Researcher
Research Interests

Molecular genetics,Zooplankton diversity,Marine healthcare,해양생물 분자유전,동물플랑크톤 다양성,해양헬스케어

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