Determination of singlet oxygen quenching and antioxidant activity of Bieckols isolated from the brown alga Eisenia bicyclis SCIE SCOPUS

Cited 7 time in WEB OF SCIENCE Cited 0 time in Scopus
Title
Determination of singlet oxygen quenching and antioxidant activity of Bieckols isolated from the brown alga Eisenia bicyclis
Author(s)
Kwon, Tae-Hyung; Suh, Hwa-Jin; Lee, In-Kyoung; Yun, Bong-Sik; Kim, Tae-Wan; Hwang, Dai-Il; Kim, You-Jeong; Kim, Min-Jeong; Kwon, Oh-Oun; Kim, Choong-Gon; Park, Nyun-Ho
KIOST Author(s)
Kim, Choong Gon(김충곤)
Publication Year
2013-10
Abstract
In this study, we determined 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activities as well as the reducing power for screening of antioxidant activity of bieckols in Eisenia bicyclis (Kjellamn) Setchell (E. bicyclis). The compounds 6,6'-bieckol, 6,8'-bieckol and 8,8'-bieckol are representative members of the phlorotannins family. The isolated bieckols displayed markedly strong DPPH and ABTS radical scavenging effects when compared to those of positive controls (BHA and Trolox). These bieckols were also found to have significant reducing power. The isolated bieckols (6,6'-bieckol, 6,8'-bieckol and 8,8'-bieckol) were found to effectively suppress the detrimental effects of O-1(2) on type-II photosensitization. The concentrations required to exert a 50 % quenching effect on O-1(2) (QC(50)) were found to be 30.7, 35.7 and 49.4 mu M for 6,6'-bieckol, 6,8'-bieckol and 8,8'-bieckol, respectively. Interestingly, all these bieckols were found to be superior to histidine (5.9 mM), a well-known O-1(2) quencher. These results suggested that brown algae phlorotannins, and bieckols in particular, may play an important role in protecting marine organisms against sunlight damage by eliminating O-1(2). This knowledge may contribute to the development of natural bioactive products with potential applications in reducing photo-produced oxidative damage involving reactive oxygen species in living organisms.
ISSN
1438-2377
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/40425
DOI
10.1007/s00217-013-2017-7
Bibliographic Citation
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, v.237, no.4, pp.501 - 508, 2013
Publisher
SPRINGER
Subject
ENZYMATIC EXTRACTS; PHLOROTANNINS; SEAWEEDS; METABOLITES; PROTEINS; DAMAGE; ASSAY
Keywords
Antioxidant; Brown alga; Eisenia bicyclis (Kjellamn) Setchell; Phlorotannins; Singlet oxygen quenching
Type
Article
Language
English
Document Type
Article
Publisher
SPRINGER
Related Researcher
Research Interests

Molecular genetics,Zooplankton diversity,Marine healthcare,해양생물 분자유전,동물플랑크톤 다양성,해양헬스케어

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