An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp 03N67 SCIE SCOPUS

Cited 21 time in WEB OF SCIENCE Cited 22 time in Scopus
Title
An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp 03N67
Author(s)
Shin, Hee Jae; Mondol, M. A. Mojid; Yu, Tae Kyung; Lee, Hyi-Seung; Lee, Yeon-Ju; Jung, Hye Jin; Kim, Jong Hyeon; Kwon, Ho Jeong
KIOST Author(s)
Shin, Hee Jae(신희재)Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)
Alternative Author(s)
신희재; Mondol Md; 이희승; 이연주
Publication Year
2010-12-17
Abstract
Cyclo-(L-Pro-L-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
ISSN
1874-3900
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3993
DOI
10.1016/j.phytol.2010.07.005
Bibliographic Citation
PHYTOCHEMISTRY LETTERS, v.3, no.4, pp.194 - 197, 2010
Publisher
ELSEVIER SCIENCE BV
Subject
IN-VITRO; DIKETOPIPERAZINES; METABOLITES; TUMORS; VIVO
Keywords
Marine actinomycetes; Angiogenesis inhibitors; HUVECs; Diketopiperazine; Cyclo-(L-Pro-L-Met)
Type
Article
Language
English
Document Type
Article
Publisher
ELSEVIER SCIENCE BV
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