Scalarane-type sesterterpenes from the Philippines sponge hyrtios sp.
SCOPUS
KCI
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Title
- Scalarane-type sesterterpenes from the Philippines sponge hyrtios sp.
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Author(s)
- Choi J.-H.; Lee H.-S.; Campos W.L.
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
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Alternative Author(s)
- 최재형; 이희승
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Publication Year
- 2020-03
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Abstract
- The marine sponge Hyrtios sp. collected in the Philippines was extracted and partitioned. The resulting organic layer was purified by C18 reversed-phase column chromatography and HPLC to achieve the separation of nine scalarane-type sesterterpenes, including one new compound with eight known sca-larane analogs. The chemical structures of the isolated compounds 1−9 were elucidated by 1D and 2D NMR and MS data analysis. All nine compounds were evaluated for their antibacterial activities against three Gram-positive and three Gram-negative bacteria. The compound 3 exhibited potent antibacterial activities against Bacillus subtilis and Micrococcus luteus. The compounds 7 and 9 displayed considerable activities against Bacillus subtilis and the others had moderate results. © 2020, Korea Institute of Ocean Science and Technology. All rights reserved.
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ISSN
- 1598-141X
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/38825
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DOI
- 10.4217/OPR.2020.42.1.015
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Bibliographic Citation
- Ocean and Polar Research, v.42, no.1, pp.15 - 20, 2020
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Publisher
- Korea Institute of Ocean Science and Technology
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Keywords
- Antibacterial activities; Hyrtios sp; Marine sponge; Scalarane; Sesterterpene
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Type
- Article
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Language
- English
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Document Type
- Article
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