Transcriptional response of marine medaka (Oryzias javanicus) on exposure to toxaphene SCIE SCOPUS
DC Field | Value | Language |
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dc.contributor.author | Woo, Seonock | - |
dc.contributor.author | Yum, Seungshic | - |
dc.date.accessioned | 2020-04-20T07:44:00Z | - |
dc.date.available | 2020-04-20T07:44:00Z | - |
dc.date.created | 2020-01-28 | - |
dc.date.issued | 2011-04 | - |
dc.identifier.issn | 1532-0456 | - |
dc.identifier.uri | https://sciwatch.kiost.ac.kr/handle/2020.kiost/3881 | - |
dc.description.abstract | Differential gene expression profiles were established from the head and liver tissues of the marine medaka fish (Olyzias javanicus) after its exposure to toxaphene, a persistent organic pollutant and insecticide, using differential display polymerase chain reaction. Twenty-seven differentially expressed genes were identified, which were associated with the cytoskeleton, development, metabolism, nucleic acid/protein binding, and signal transduction. Among these genes, those encoding molecular biomarkers known to be involved in metabolism, ATP hydrolysis, and protein regulation were strongly induced at the transcription level, and genes encoding one structural protein subunit or involved in lipid metabolism were strongly downregulated. The same trends in gene expression changes were observed with real-time PCR analysis of 12 selected clones. The genes identified could be used as molecular biomarkers of biological responses to polychlorinated camphene contamination in aquatic environments. (C) 2011 Elsevier Inc. All rights reserved. | - |
dc.description.uri | 1 | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | DIFFERENTIAL GENE-EXPRESSION | - |
dc.subject | HETEROLOGOUS MICROARRAY HYBRIDIZATION | - |
dc.subject | HOMOCYSTEINE S-METHYLTRANSFERASE | - |
dc.subject | HUMAN HEALTH IMPLICATIONS | - |
dc.subject | ENVIRONMENTAL CONTAMINANTS | - |
dc.subject | JAVANESE MEDAKA | - |
dc.subject | ARCTIC CANADA | - |
dc.subject | REGENERATION | - |
dc.subject | CRYSTALLINS | - |
dc.subject | METABOLISM | - |
dc.title | Transcriptional response of marine medaka (Oryzias javanicus) on exposure to toxaphene | - |
dc.type | Article | - |
dc.citation.endPage | 361 | - |
dc.citation.startPage | 355 | - |
dc.citation.title | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | - |
dc.citation.volume | 153 | - |
dc.citation.number | 3 | - |
dc.contributor.alternativeName | 우선옥 | - |
dc.contributor.alternativeName | 염승식 | - |
dc.identifier.bibliographicCitation | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v.153, no.3, pp.355 - 361 | - |
dc.identifier.doi | 10.1016/j.cbpc.2010.12.006 | - |
dc.identifier.scopusid | 2-s2.0-79951513043 | - |
dc.identifier.wosid | 000288298700012 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DIFFERENTIAL GENE-EXPRESSION | - |
dc.subject.keywordPlus | HETEROLOGOUS MICROARRAY HYBRIDIZATION | - |
dc.subject.keywordPlus | HOMOCYSTEINE S-METHYLTRANSFERASE | - |
dc.subject.keywordPlus | HUMAN HEALTH IMPLICATIONS | - |
dc.subject.keywordPlus | ENVIRONMENTAL CONTAMINANTS | - |
dc.subject.keywordPlus | JAVANESE MEDAKA | - |
dc.subject.keywordPlus | ARCTIC CANADA | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | CRYSTALLINS | - |
dc.subject.keywordPlus | METABOLISM | - |
dc.subject.keywordAuthor | Oryzias javanicus | - |
dc.subject.keywordAuthor | Marine medaka | - |
dc.subject.keywordAuthor | Toxaphene | - |
dc.subject.keywordAuthor | Polychlorinated camphenes (PCCs) | - |
dc.subject.keywordAuthor | Differential gene expression profile | - |
dc.subject.keywordAuthor | Differential display (DD-) PCR | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Zoology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalResearchArea | Zoology | - |