Transcriptional response of marine medaka (Oryzias javanicus) on exposure to toxaphene SCIE SCOPUS

DC Field Value Language
dc.contributor.author Woo, Seonock -
dc.contributor.author Yum, Seungshic -
dc.date.accessioned 2020-04-20T07:44:00Z -
dc.date.available 2020-04-20T07:44:00Z -
dc.date.created 2020-01-28 -
dc.date.issued 2011-04 -
dc.identifier.issn 1532-0456 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/3881 -
dc.description.abstract Differential gene expression profiles were established from the head and liver tissues of the marine medaka fish (Olyzias javanicus) after its exposure to toxaphene, a persistent organic pollutant and insecticide, using differential display polymerase chain reaction. Twenty-seven differentially expressed genes were identified, which were associated with the cytoskeleton, development, metabolism, nucleic acid/protein binding, and signal transduction. Among these genes, those encoding molecular biomarkers known to be involved in metabolism, ATP hydrolysis, and protein regulation were strongly induced at the transcription level, and genes encoding one structural protein subunit or involved in lipid metabolism were strongly downregulated. The same trends in gene expression changes were observed with real-time PCR analysis of 12 selected clones. The genes identified could be used as molecular biomarkers of biological responses to polychlorinated camphene contamination in aquatic environments. (C) 2011 Elsevier Inc. All rights reserved. -
dc.description.uri 1 -
dc.language English -
dc.publisher ELSEVIER SCIENCE INC -
dc.subject DIFFERENTIAL GENE-EXPRESSION -
dc.subject HETEROLOGOUS MICROARRAY HYBRIDIZATION -
dc.subject HOMOCYSTEINE S-METHYLTRANSFERASE -
dc.subject HUMAN HEALTH IMPLICATIONS -
dc.subject ENVIRONMENTAL CONTAMINANTS -
dc.subject JAVANESE MEDAKA -
dc.subject ARCTIC CANADA -
dc.subject REGENERATION -
dc.subject CRYSTALLINS -
dc.subject METABOLISM -
dc.title Transcriptional response of marine medaka (Oryzias javanicus) on exposure to toxaphene -
dc.type Article -
dc.citation.endPage 361 -
dc.citation.startPage 355 -
dc.citation.title COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY -
dc.citation.volume 153 -
dc.citation.number 3 -
dc.contributor.alternativeName 우선옥 -
dc.contributor.alternativeName 염승식 -
dc.identifier.bibliographicCitation COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v.153, no.3, pp.355 - 361 -
dc.identifier.doi 10.1016/j.cbpc.2010.12.006 -
dc.identifier.scopusid 2-s2.0-79951513043 -
dc.identifier.wosid 000288298700012 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus DIFFERENTIAL GENE-EXPRESSION -
dc.subject.keywordPlus HETEROLOGOUS MICROARRAY HYBRIDIZATION -
dc.subject.keywordPlus HOMOCYSTEINE S-METHYLTRANSFERASE -
dc.subject.keywordPlus HUMAN HEALTH IMPLICATIONS -
dc.subject.keywordPlus ENVIRONMENTAL CONTAMINANTS -
dc.subject.keywordPlus JAVANESE MEDAKA -
dc.subject.keywordPlus ARCTIC CANADA -
dc.subject.keywordPlus REGENERATION -
dc.subject.keywordPlus CRYSTALLINS -
dc.subject.keywordPlus METABOLISM -
dc.subject.keywordAuthor Oryzias javanicus -
dc.subject.keywordAuthor Marine medaka -
dc.subject.keywordAuthor Toxaphene -
dc.subject.keywordAuthor Polychlorinated camphenes (PCCs) -
dc.subject.keywordAuthor Differential gene expression profile -
dc.subject.keywordAuthor Differential display (DD-) PCR -
dc.relation.journalWebOfScienceCategory Biochemistry & Molecular Biology -
dc.relation.journalWebOfScienceCategory Endocrinology & Metabolism -
dc.relation.journalWebOfScienceCategory Toxicology -
dc.relation.journalWebOfScienceCategory Zoology -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Biochemistry & Molecular Biology -
dc.relation.journalResearchArea Endocrinology & Metabolism -
dc.relation.journalResearchArea Toxicology -
dc.relation.journalResearchArea Zoology -
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