Ieodomycins A-D, Antimicrobial Fatty Acids from a Marine Bacillus sp.
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Title
- Ieodomycins A-D, Antimicrobial Fatty Acids from a Marine Bacillus sp.
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Author(s)
- Mondol, M. A. Mojid; Kim, Ji Hye; Lee, Min Ah; Tareq, Fakir Shahidullah; Lee, Hyi-Seung; Lee, Yeon-Ju; Shin, Hee Jae
- KIOST Author(s)
- Lee, Min Ah(이민아); Lee, Hyi Seung(이희승); Lee, Yeon Ju(이연주); Shin, Hee Jae(신희재)
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Alternative Author(s)
- Mondol Md; 김지혜; 이민아; TAREQ; 이희승; 이연주; 신희재
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Publication Year
- 2011-07
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Abstract
- Bioassay-guided isolation of the EtOAc extract of a marine Bacillus sp., cultured in modified Bennett's broth medium, yielded four new antimicrobial fatty acids, named ieodomycins A-D (1-4). The planar structures of these new compounds were determined by extensive 1D and 2D NMR and HRESIMS spectroscopic data analysis. Their absolute configurations were elucidated by modified Mosher's method and literature data review. All four new compounds (1-4) demonstrated antimicrobial activities in vitro.
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ISSN
- 0163-3864
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/3852
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DOI
- 10.1021/np200223r
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Bibliographic Citation
- JOURNAL OF NATURAL PRODUCTS, v.74, no.7, pp.1606 - 1612, 2011
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Publisher
- AMER CHEMICAL SOC
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Subject
- UNIVERSAL NMR DATABASE; NATURAL-PRODUCTS; STEREOCHEMICAL ASSIGNMENT; ANTIBACTERIAL ACTIVITY; DESERTOMYCIN/OASOMYCIN CLASS; ANTIBIOTICS; BACTERIA; CREATION; WATER
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Type
- Article
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Language
- English
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Document Type
- Article
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