Transcriptional analysis of disk abalone (Haliotis discus discus) antioxidant enzymes against marine bacteria and virus challenge SCIE SCOPUS

DC Field Value Language
dc.contributor.author De Zoysa, Mahanama -
dc.contributor.author Whang, Ilson -
dc.contributor.author Nikapitiya, Chamilani -
dc.contributor.author Oh, Chulhong -
dc.contributor.author Choi, Cheol Young -
dc.contributor.author Lee, Jehee -
dc.date.accessioned 2020-04-20T07:43:44Z -
dc.date.available 2020-04-20T07:43:44Z -
dc.date.created 2020-01-28 -
dc.date.issued 2011-07 -
dc.identifier.issn 1050-4648 -
dc.identifier.uri https://sciwatch.kiost.ac.kr/handle/2020.kiost/3849 -
dc.description.abstract Diverse antioxidant enzymes are essential for marine organisms to overcome oxidative stress as well as for the fine-tuning of immune reactions through activating different signal transduction pathways. This study describes the transcriptional analysis of antioxidant enzymes of disk abalone by challenging with bacteria (Vibrio alginolyticus, Vibrio parahemolyticus, and Listeria monocytogenes) and viral hemorrhagic septicemia virus (VHSV). Upon bacteria and VHSV challenge, Manganese superoxide dismutase (MnSOD), Copper, Zinc superoxide dismutase (CuZnSOD), catalase, thioredoxin peroxidase (TPx), Selenium-dependent glutathione peroxidase (SeGPx), and thioredoxin-2 (TRx-2) expression levels were altered in gills, and hemocytes at different magnitudes. In gills, only MnSOD, catalase, and SeGPx genes were completely upregulated by post-challenge of bacterial and VHSV. Among them, SeGPx demonstrated strong upregulation by 16-fold (bacteria) and 2-fold (VHSV) in gills, and 5-fold (bacteria) and 3.0-fold (VHSV) in hemocytes. None of the genes examined were downregulated (in gills and hemocytes) by bacteria challenge even though CuZnSOD and TPx showed downregulation (completely) in hemocytes by VHSV. In general, abalone hemocytes had lower potential to induce antioxidant enzyme transcripts upon bacteria and VHSV challenge than gills. Based upon these results, we suggest that abalones induce oxidative stress in tissues during the bacteria and VHSV challenge, and the identified response of antioxidant enzymes could be supported for maintaining a low-level of reactive oxygen species (ROS) that may serve as a signal for activating immune reactions against pathogenic conditions. (C) 2011 Elsevier Ltd. All rights reserved. -
dc.description.uri 1 -
dc.language English -
dc.publisher ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD -
dc.subject DIVERSICOLOR-SUPERTEXTA -
dc.subject VIBRIO-PARAHAEMOLYTICUS -
dc.subject DEFENSE-MECHANISMS -
dc.subject OXIDATIVE STRESS -
dc.subject IMMUNE-RESPONSES -
dc.subject GENE-EXPRESSION -
dc.subject LEUKOCYTES -
dc.subject HEMOCYTES -
dc.subject INFECTION -
dc.subject PARASITE -
dc.title Transcriptional analysis of disk abalone (Haliotis discus discus) antioxidant enzymes against marine bacteria and virus challenge -
dc.type Article -
dc.citation.endPage 160 -
dc.citation.startPage 155 -
dc.citation.title FISH & SHELLFISH IMMUNOLOGY -
dc.citation.volume 31 -
dc.citation.number 1 -
dc.contributor.alternativeName 오철홍 -
dc.identifier.bibliographicCitation FISH & SHELLFISH IMMUNOLOGY, v.31, no.1, pp.155 - 160 -
dc.identifier.doi 10.1016/j.fsi.2011.04.001 -
dc.identifier.scopusid 2-s2.0-79957869726 -
dc.identifier.wosid 000292407900019 -
dc.type.docType Article -
dc.description.journalClass 1 -
dc.subject.keywordPlus DIVERSICOLOR-SUPERTEXTA -
dc.subject.keywordPlus VIBRIO-PARAHAEMOLYTICUS -
dc.subject.keywordPlus DEFENSE-MECHANISMS -
dc.subject.keywordPlus OXIDATIVE STRESS -
dc.subject.keywordPlus IMMUNE-RESPONSES -
dc.subject.keywordPlus GENE-EXPRESSION -
dc.subject.keywordPlus LEUKOCYTES -
dc.subject.keywordPlus HEMOCYTES -
dc.subject.keywordPlus INFECTION -
dc.subject.keywordPlus PARASITE -
dc.subject.keywordAuthor Antioxidant enzymes -
dc.subject.keywordAuthor Disk abalone (Haliotis discus discus) -
dc.subject.keywordAuthor ROS -
dc.subject.keywordAuthor Bacteria -
dc.subject.keywordAuthor VHSV -
dc.relation.journalWebOfScienceCategory Fisheries -
dc.relation.journalWebOfScienceCategory Immunology -
dc.relation.journalWebOfScienceCategory Marine & Freshwater Biology -
dc.relation.journalWebOfScienceCategory Veterinary Sciences -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Fisheries -
dc.relation.journalResearchArea Immunology -
dc.relation.journalResearchArea Marine & Freshwater Biology -
dc.relation.journalResearchArea Veterinary Sciences -
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