Triterpene Galactosides of the Pouoside Class and Corresponding Aglycones from the Sponge Lipastrotethya sp.
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Title
- Triterpene Galactosides of the Pouoside Class and Corresponding Aglycones from the Sponge Lipastrotethya sp.
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Author(s)
- Lee, Jung-Ho; Jang, Kyoung Hwa; Lee, Yeon-Ju; Lee, Hyi-Seung; Sim, Chung J.; Oh, Ki-Bong; Shin, Jongheon
- KIOST Author(s)
- Lee, Yeon Ju(이연주); Lee, Hyi Seung(이희승)
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Alternative Author(s)
- 이연주; 이희승
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Publication Year
- 2011-12
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Abstract
- Nine new triterpene galactosides and aglycones, along with three known compounds from the rare pouoside class, were isolated from the tropical sponge Lipastrotethya sp. collected from Micronesia. The structures of these new compounds were determined by combined spectroscopic methods and designated as pouosides F-I (4, 8, 10, and 12) and pouogenins A-E (5-7, 9, and 11). The absolute configurations of the asymmetric centers and the cyclohexenone moiety, which had been previously undetermined, were assigned by NOESY analyses and Mosher's methods. Several of these compounds exhibited weak cytotoxicity against the K562 cell line.
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ISSN
- 0163-3864
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URI
- https://sciwatch.kiost.ac.kr/handle/2020.kiost/3792
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DOI
- 10.1021/np200748g
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Bibliographic Citation
- JOURNAL OF NATURAL PRODUCTS, v.74, no.12, pp.2563 - 2570, 2011
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Publisher
- AMER CHEMICAL SOC
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Subject
- MARINE SPONGE; ASTEROPUS-SARASINOSUM; SAPONINS; GROWTH; ASSAY
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Type
- Article
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Language
- English
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Document Type
- Article
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