Triterpene Galactosides of the Pouoside Class and Corresponding Aglycones from the Sponge Lipastrotethya sp. SCIE SCOPUS

Cited 11 time in WEB OF SCIENCE Cited 12 time in Scopus
Title
Triterpene Galactosides of the Pouoside Class and Corresponding Aglycones from the Sponge Lipastrotethya sp.
Author(s)
Lee, Jung-Ho; Jang, Kyoung Hwa; Lee, Yeon-Ju; Lee, Hyi-Seung; Sim, Chung J.; Oh, Ki-Bong; Shin, Jongheon
KIOST Author(s)
Lee, Yeon Ju(이연주)Lee, Hyi Seung(이희승)
Publication Year
2011-12
Abstract
Nine new triterpene galactosides and aglycones, along with three known compounds from the rare pouoside class, were isolated from the tropical sponge Lipastrotethya sp. collected from Micronesia. The structures of these new compounds were determined by combined spectroscopic methods and designated as pouosides F-I (4, 8, 10, and 12) and pouogenins A-E (5-7, 9, and 11). The absolute configurations of the asymmetric centers and the cyclohexenone moiety, which had been previously undetermined, were assigned by NOESY analyses and Mosher's methods. Several of these compounds exhibited weak cytotoxicity against the K562 cell line.
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3792
DOI
10.1021/np200748g
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.74, no.12, pp.2563 - 2570, 2011
Publisher
AMER CHEMICAL SOC
Subject
MARINE SPONGE; ASTEROPUS-SARASINOSUM; SAPONINS; GROWTH; ASSAY
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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