Cyclic Ether-Containing Macrolactins, Antimicrobial 24-Membered Isomeric Macrolactones from a Marine Bacillus sp. SCIE SCOPUS

Cited 43 time in WEB OF SCIENCE Cited 46 time in Scopus
Title
Cyclic Ether-Containing Macrolactins, Antimicrobial 24-Membered Isomeric Macrolactones from a Marine Bacillus sp.
Author(s)
Mondol, M. A. Mojid; Tareq, Fakir Shahidullah; Kim, Ji Hye; Lee, Min Ah; Lee, Hyi-Seung; Lee, Yeon-Ju; Lee, Jong Seok; Shin, Hee Jae
KIOST Author(s)
Lee, Min Ah(이민아)Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)Lee, Jong Seok(이종석)Shin, Hee Jae(신희재)
Alternative Author(s)
Mondol Md; TAREQ; 김지혜; 이민아; 이희승; 이연주; 이종석; 신희재
Publication Year
2011-12
Abstract
Bioassay-guided isolation of bioactive metabolites from the ethyl acetate extract of a marine Bacillus sp. fermentation broth has led to the discovery of three new 24-membered macrolactones, macrolactins 1-3, which contain an oxetane, an epoxide, and a tetrahydropyran ring, respectively. The configurations of 1-3 were assigned by a combination of coupling constants, ROESY data analysis, and application of the modified Mosher's method. Compounds 1-3 showed in vitro antimicrobial activity.
ISSN
0163-3864
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3783
DOI
10.1021/np200487k
Bibliographic Citation
JOURNAL OF NATURAL PRODUCTS, v.74, no.12, pp.2582 - 2587, 2011
Publisher
AMER CHEMICAL SOC
Subject
BACTERIUM; ANTIBACTERIAL; ACID
Type
Article
Language
English
Document Type
Article
Publisher
AMER CHEMICAL SOC
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