Synthesis and antimicrobial activity of brominated resorcinol dimers SCIE SCOPUS
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- Title
- Synthesis and antimicrobial activity of brominated resorcinol dimers
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
- Alternative Author(s)
- 박승일; 이희승
- Publication Year
- 2011-12-01
- Abstract
- Dibrominated resorcinol dimers were synthesized by reaction of 4-bromoresorcinol with aldehydes under reflux in ethanol in the presence of HCl. Subsequent dehalogenation yielded the corresponding monobrominated compounds and a fully dehalogenated dimer. Of the dimers, 6,6'-((4-hydroxyphenyl)methylene)bis(4-bromobenzene-1,3-diol) (4) displayed potent antibacterial activity and inhibitory activity against isocitrate lyase Candida albicans. (C) 2011 Elsevier Ltd. All rights reserved.
- ISSN
- 0960-894X
- Bibliographic Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.21, no.23, pp.7142 - 7145, 2011
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Subject
- ALGA SYMPHYOCLADIA-LATIUSCULA; ISOCITRATE LYASE INHIBITORS; RED ALGA; ODONTHALIA-CORYMBIFERA; RHODOMELA-CONFERVOIDES; CANDIDA-ALBICANS; LIVING CELLS; BROMOPHENOLS; CONDENSATION; 2,4-DIHYDROXYDIPHENYLMETHANE
- Keywords
- Resorcinol; Bromophenol; Red alga; Antibacterial activity; Antifungal activity
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
