IDENTIFICATION OF NEW POLYPRENYL HYDROQUINONE DERIVATIVES FROM TROPICAL MARINE SPONGE IRCINIA SP. SCIE SCOPUS
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- Title
- IDENTIFICATION OF NEW POLYPRENYL HYDROQUINONE DERIVATIVES FROM TROPICAL MARINE SPONGE IRCINIA SP.
- KIOST Author(s)
- Lee, Hyi Seung(이희승); Lee, Yeon Ju(이연주); Shin, Hee Jae(신희재); Lee, Jong Seok(이종석); Heo, Soo Jin(허수진)
- Alternative Author(s)
- 이희승; 이연주; 이종욱; 신희재; 이종석; 허수진
- Publication Year
- 2012-06-01
- Abstract
- Chemical investigations of the tropical marine sponge of the genus Ircinia have resulted in the isolation of three new polyprenyl chromenes (1-3), together with known hydroquinone derivatives (4-9). Their structures were elucidated on the basis of mass spectrometry and detailed 2D NMR spectroscopic data. The anti-inflammatory activity of these compounds was evaluated. Compounds 7, 8, and 9 exhibited moderate inhibition of LPS-induced NO production in RAW 264.7 macrophages.
- ISSN
- 0385-5414
- Bibliographic Citation
- HETEROCYCLES, v.85, no.6, pp.1437 - 1446, 2012
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Subject
- BROWN ALGA; SARGASSUM-SILIQUASTRUM; TORTILE; CELLS
- Keywords
- Tropical Sponge; Ircinia species; Polyprenyl Hydroquinone; Chromene; Anti-Inflammatory Activity
- Type
- Article
- Language
- English
- Document Type
- Article
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- There are no files associated with this item.
