IDENTIFICATION OF NEW POLYPRENYL HYDROQUINONE DERIVATIVES FROM TROPICAL MARINE SPONGE IRCINIA SP. SCIE SCOPUS

Cited 2 time in WEB OF SCIENCE Cited 2 time in Scopus
Title
IDENTIFICATION OF NEW POLYPRENYL HYDROQUINONE DERIVATIVES FROM TROPICAL MARINE SPONGE IRCINIA SP.
Author(s)
Lee, Hyi-Seung; Lee, Yeon-Ju; Lee, Jong Wook; Shin, Hee Jae; Lee, Jong Seok; Kim, Kil-Nam; Yoon, Weon-Jong; Heo, Soo-Jin; Kim, Hye-Kyeong
KIOST Author(s)
Lee, Hyi Seung(이희승)Lee, Yeon Ju(이연주)Lee, Jong Soo(이종수)Heo, Soo Jin(허수진)
Publication Year
2012-06-01
Abstract
Chemical investigations of the tropical marine sponge of the genus Ircinia have resulted in the isolation of three new polyprenyl chromenes (1-3), together with known hydroquinone derivatives (4-9). Their structures were elucidated on the basis of mass spectrometry and detailed 2D NMR spectroscopic data. The anti-inflammatory activity of these compounds was evaluated. Compounds 7, 8, and 9 exhibited moderate inhibition of LPS-induced NO production in RAW 264.7 macrophages.
ISSN
0385-5414
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3577
DOI
10.3987/COM-12-12454
Bibliographic Citation
HETEROCYCLES, v.85, no.6, pp.1437 - 1446, 2012
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Subject
BROWN ALGA; SARGASSUM-SILIQUASTRUM; TORTILE; CELLS
Keywords
Tropical Sponge; Ircinia species; Polyprenyl Hydroquinone; Chromene; Anti-Inflammatory Activity
Type
Article
Language
English
Document Type
Article
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Related Researcher
Research Interests

Marine Natural Products,Organic Chemistry,해양천연물,유기화학

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