Acremolin, a new 1H-azirine metabolite from the marine-derived fungus Acremonium strictum SCIE SCOPUS

Cited 31 time in WEB OF SCIENCE Cited 31 time in Scopus
Title
Acremolin, a new 1H-azirine metabolite from the marine-derived fungus Acremonium strictum
Author(s)
Julianti, Elin; Oh, Hana; Lee, Hyi-Seung; Oh, Dong-Chan; Oh, Ki-Bong; Shin, Jongheon
KIOST Author(s)
Lee, Hyi Seung(이희승)
Publication Year
2012-06-06
Abstract
Acremolin (1), a novel modified base, was isolated from the culture broth of the marine fungus Acremonium strictum. Based on combined spectroscopic analyses, the structure of this compound was that of a methyl guanine base containing an isoprene unit. In addition, the presence of a 1H-azirine moiety is unprecedented among natural products. This compound exhibited weak cytotoxicity against an A549 cell line. (C) 2012 Elsevier Ltd. All rights reserved.
ISSN
0040-4039
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3552
DOI
10.1016/j.tetlet.2012.03.133
Bibliographic Citation
TETRAHEDRON LETTERS, v.53, no.23, pp.2885 - 2886, 2012
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Subject
RESOURCE; BACTERIA
Keywords
Acremolin; A modified base; 1H-Azirine functionality; Marine fungus; Acremonium strictum
Type
Article
Language
English
Document Type
Article
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
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