Acremolin, a new 1H-azirine metabolite from the marine-derived fungus Acremonium strictum SCIE SCOPUS
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- Title
- Acremolin, a new 1H-azirine metabolite from the marine-derived fungus Acremonium strictum
- KIOST Author(s)
- Lee, Hyi Seung(이희승)
- Alternative Author(s)
- 이희승
- Publication Year
- 2012-06-06
- Abstract
- Acremolin (1), a novel modified base, was isolated from the culture broth of the marine fungus Acremonium strictum. Based on combined spectroscopic analyses, the structure of this compound was that of a methyl guanine base containing an isoprene unit. In addition, the presence of a 1H-azirine moiety is unprecedented among natural products. This compound exhibited weak cytotoxicity against an A549 cell line. (C) 2012 Elsevier Ltd. All rights reserved.
- ISSN
- 0040-4039
- Bibliographic Citation
- TETRAHEDRON LETTERS, v.53, no.23, pp.2885 - 2886, 2012
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Subject
- RESOURCE; BACTERIA
- Keywords
- Acremolin; A modified base; 1H-Azirine functionality; Marine fungus; Acremonium strictum
- Type
- Article
- Language
- English
- Document Type
- Article
- Files in This Item:
- There are no files associated with this item.
