Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp. SCIE SCOPUS

Cited 8 time in WEB OF SCIENCE Cited 9 time in Scopus
Title
Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp.
Author(s)
Lee, Yeon-Ju; Yoo, Su-Jung; Kang, Jong Soon; Yun, Jieun; Shin, Hee Jae; Lee, Jong Seok; Lee, Hyi-Seung
KIOST Author(s)
Lee, Yeon Ju(이연주)Shin, Hee Jae(신희재)Lee, Jong Seok(이종석)Lee, Hyi Seung(이희승)
Alternative Author(s)
이연주; 유수정; 신희재; 이종석; 이희승
Publication Year
2013-01
Abstract
A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher's method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C-16.
ISSN
0024-4201
URI
https://sciwatch.kiost.ac.kr/handle/2020.kiost/3280
DOI
10.1007/s11745-012-3727-5
Bibliographic Citation
LIPIDS, v.48, no.1, pp.87 - 91, 2013
Publisher
SPRINGER HEIDELBERG
Subject
POLYACETYLENES; ACIDS
Keywords
Sponge; Petrosia; Polyacetylenic alcohol; Petrosiacetylene; Cytotoxicity
Type
Article
Language
English
Document Type
Article
Publisher
SPRINGER HEIDELBERG
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